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Advances in Hematopoietic Stem Cell Research
Edited by Rosana Pelayo, ISBN 978-953-307-930-1, Hard cover, 464 pages, Publisher: InTech, Published: January 27, 2012 under CC BY 3.0 license, in subject Oncology
DOI: 10.5772/1203
This book provides a comprehensive overview in our understanding of the biology and therapeutic potential of hematopoietic stem cells, and is aimed at those engaged in stem cell research: undergraduate and postgraduate science students, investigators and clinicians. Starting from fundamental principles in hematopoiesis, Advances in Hematopoietic Stem Cell Research assemble a wealth of information relevant to central mechanisms that may regulate differentiation, and expansion of hematopoietic stem cells in normal conditions and during disease.
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Book contents
- Chapter 1Networks Establishing Hematopoietic Stem Cell Multipotency and Self-Renewal
- Chapter 2Regulation of Hematopoietic Stem Cell Fate: Self-Renewal, Quiescence and Survival
- Chapter 3Transcriptional Quiescence of Hematopoietic Stem Cells
- Chapter 4Markers for Hematopoietic Stem Cells: Histories and Recent Achievements
- Chapter 5Interferon Regulatory Factor-2 Regulates Hematopoietic Stem Cells in Mouse Bone Marrow
- Chapter 6Regulation of Tyrosine Kinase Signaling by Cbl in Hematopoietic Stem Cells
- Chapter 7The Hypoxia Regulatory System in Hematopoietic Stem Cells
- Chapter 8Skeletogenesis and the Hematopoietic Niche
- Chapter 9Molecular Mechanisms Underlying Bone Marrow Homing of Hematopoietic Stem Cells
- Chapter 10Searching for the Key to Expand Hematopoietic Stem Cells
- Chapter 11Insights Into Stem Cell Aging
- Chapter 12Hematopoietic Stem Cell in Acute Myeloid Leukemia Development
- Chapter 13From HSC to B-Lymphoid Cells in Normal and Malignant Hematopoiesis
- Chapter 14Distribution of SDF1-3’A, GNB3 C825T and MMP-9 C-1562T Polymorphisms in HSC CD34+ from Peripheral Blood of Patients with Hematological Malignancies
- Chapter 15Hematopoietic Derived Fibrocytes: Emerging Effector Cells in Fibrotic Disorders
- Chapter 16Hematopoietic Stem Cells Therapeutic Applications
- Chapter 17Hematopoietic Stem Cell Potency for Cellular Therapeutic Transplantation
- Chapter 18Detection of CMV Infection in Allogeneic SCT Recipients: The Multiple Assays
- Chapter 19Bone Marrow Derived Pluripotent Stem Cells in Ischemic Heart Disease: Bridging the Gap Between Basic Research and Clinical Applications
- Chapter 20Gene Therapy of Hematopoietic and Immune Systems: Current State and Perspectives
