Open access peer-reviewed Edited Volume

Varicella Zoster Virus

Khalid Ahmed Al-Anazi

King Fahad Specialist Hospital


Virus Genome Different Genotypes Risk Factors Clinical Manifestations Bone Marrow Stimulation Graft Versus Host Disease Mesenchymal Stem Cells Natural Killer Cells Open Reading Frames Glycoproteins Extracellular Vesicles Exosomes

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About the book

The book will be an updated review on varicella zoster virus (VZV). It will include several sections covering various aspects of the virus. The virus genome, the various genotypes, epigenetic control, and the differences between VZV and other herpes viruses will be highlighted. Also, animal and experimental models of the virus will be discussed. The clinical manifestations and complications of VZV infections in immunocompromised individuals will be discussed thoroughly. However, VZV infection in patients with hematologic malignancies, bone marrow failure, and solid tumors in addition to recipients of various forms of hematopoietic stem cell transplantation will be given special attention. The diagnosis of VZV infections, treatment, vaccination and antiviral prophylaxis in this group of patients will be discussed in details. New literature on the pathogenesis of VZV infections including the cells involved, cellular proteins, extracellular vesicles, micro-RNAs, cytokines, interferons, and signaling pathways will be included. The emerging role of the virus in virotherapy, as well as the recently reported beneficial effects of the virus in immunocompromised hosts such as stimulation of bone marrow activity, antitumor effects, and associations with graft versus host disease, will receive particular attention due to the possible future implications of such discoveries in the treatment of immunocompromised patients.

Publishing process

Book initiated and editor appointed

Date completed: November 18th 2019

Applications to edit the book are assessed and a suitable editor is selected, at which point the process begins.

Chapter proposals submitted and reviewed

Deadline for chapter proposals: December 9th 2019

Potential authors submit chapter proposals ready for review by the academic editor and our publishing review team.

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Approved chapters written in full and submitted

Deadline for full chapters: February 7th 2020

Once approved by the academic editor and publishing review team, chapters are written and submitted according to pre-agreed parameters

Full chapters peer reviewed

Review results due: April 27th 2020

Full chapter manuscripts are screened for plagiarism and undergo a Main Editor Peer Review. Results are sent to authors within 30 days of submission, with suggestions for rounds of revisions.

Book compiled, published and promoted

Expected publication date: June 26th 2020

All chapters are copy-checked and typesetted before being published. IntechOpen regularly submits its books to major databases for evaluation and coverage, including the Clarivate Analytics Book Citation Index in the Web of ScienceTM Core Collection. Other discipline-specific databases are also targeted, such as Web of Science's BIOSIS Previews.

About the editor

Khalid Ahmed Al-Anazi

King Fahad Specialist Hospital

Dr. Khalid Ahmed Al-Anazi is a consultant Hemato-Oncologist and the Chairman of the Department of Adult Hematology and Hematopoietic Stem Cell Transplantation (HSCT) at King Fahad Specialist Hospital (KFSH) in Dammam, Saudi Arabia. He graduated from the college of medicine, King Saud University (KSU) in Riyadh in 1986. After having his Boards in Internal Medicine, he trained in clinical hematology and HSCT at King’s College Hospital, University of London, U.K. He has 4 year experience in internal medicine and 28 year experience in adult clinical hematology and HSCT at: Riyadh Armed Forces Hospital; King Faisal Specialist Hospital and Research Centre (KFSH&RC) in Riyadh; King Khalid University Hospital (KKUH) and the College of Medicine, KSU in Riyadh; and KFSH in Dammam, Saudi Arabia. He established the adult HSCT program at KFSH in Dammam in the year 2010. He received the award of the best teacher in the Department of Medicine, at the College of Medicine and KKUH in Riyadh in the year 2014. He has more than 95 publications including retrospective studies, review articles, book chapters, and electronic books and he is a reviewer for 25 international medical journals. He is the Editor-in-Chief of the Journal of Stem Cell Biology and Transplantation and the Journal of Molecular Genetics and Medicine in addition to being Associate Editor for 26 other medical journals in HSCT, hematology, cancer and infectious diseases. He is a member of several international organizations including ECIL (European Conference of Infections in Leukemia).

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Book chapters authored 9

Books edited 1

Introducing your Author Service Manager

Ms. Marijana Francetic

As an Author Service Manager my responsibilities include monitoring and facilitating all publishing activities for authors and editors. From chapter submission and review, to approval and revision, copyediting and design, until final publication, I work closely with authors and editors to ensure a simple and easy publishing process. I maintain constant and effective communication with authors, editors and reviewers, which allows for a level of personal support that enables contributors to fully commit and concentrate on the chapters they are writing, editing, or reviewing. I assist authors in the preparation of their full chapter submissions and track important deadlines and ensure they are met. I help to coordinate internal processes such as linguistic review, and monitor the technical aspects of the process. As an ASM I am also involved in the acquisition of editors. Whether that be identifying an exceptional author and proposing an editorship collaboration, or contacting researchers who would like the opportunity to work with IntechOpen, I establish and help manage author and editor acquisition and contact.

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