About the book
Coronavirus (SARS-CoV-2) brought the world economies to their knees; we now know that viruses can be as destructive as nuclear weapons. Coronavirus disease (COVID-19) is causing a major once-in-a-century global pandemic. SARS-CoV-2 enters host cells through the binding of a cellular receptor angiotensin-converting enzyme 2 (ACE2).
Literature showed the presence of ACE2 receptors on the membrane of erythrocyte or red blood cell (RBC), indicating that erythrocyte (RBC) can be considered as a peripheral biomarker for SARS-C0V2 infection.
Increased levels of glycolysis and fragmentation of RBC membrane proteins were observed in the SARS-C0V2 infected patients, demonstrating that not only RBC’s metabolism and proteome but its membrane lipidome could be influenced by SARS-C0V2 infection changing the homeostasis of the infected erythrocyte. This altered RBC may result in the clot and thrombus formation; the major signs of critically ill Covid-19 patients.
This book is going to be a succinct source of knowledge not only for the specialists, researchers, academics and the students in this area but for the general public who are concern about the present situation and are interested in knowing about simple non-invasive measures for identifying viral and bacterial infections through their red blood cells.