Open access peer-reviewed Edited Volume

Erythrocyte - a Peripheral Biomarker for Viral and Bacterial Infections

Kaneez Fatima Shad

University of Technology Sydney

Dr. Shad is a governing body member and mentor of Women in World Neuroscience (WWN), a division of the International Brain Research Organization (IBRO). She is also a member of IBRO-APRC Global Advocacy responsible for brain research funding distribution in this region.

Covering

Spike Protein Hemoglobin Proteins for Oxygen Transport Altered Protein Structures RBC ACE Receptors RBC ACE-2 Receptors Carboxypeptidase Mas Receptor Metabolomics Gas Transport Glucose-6-Phosphate Phosphoglycerate

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About the book

Coronavirus (SARS-CoV-2) brought the world economies to their knees; we now know that viruses can be as destructive as nuclear weapons. Coronavirus disease (COVID-19) is causing a major once-in-a-century global pandemic. SARS-CoV-2 enters host cells through the binding of a cellular receptor angiotensin-converting enzyme 2 (ACE2).
Literature showed the presence of ACE2 receptors on the membrane of erythrocyte or red blood cell (RBC), indicating that erythrocyte (RBC) can be considered as a peripheral biomarker for SARS-C0V2 infection.

Increased levels of glycolysis and fragmentation of RBC membrane proteins were observed in the SARS-C0V2 infected patients, demonstrating that not only RBC’s metabolism and proteome but its membrane lipidome could be influenced by SARS-C0V2 infection changing the homeostasis of the infected erythrocyte. This altered RBC may result in the clot and thrombus formation; the major signs of critically ill Covid-19 patients.

This book is going to be a succinct source of knowledge not only for the specialists, researchers, academics and the students in this area but for the general public who are concern about the present situation and are interested in knowing about simple non-invasive measures for identifying viral and bacterial infections through their red blood cells.

Publishing process

Book initiated and editor appointed

Date completed: October 15th 2020

Applications to edit the book are assessed and a suitable editor is selected, at which point the process begins.

Chapter proposals submitted and reviewed

Deadline for chapter proposals: November 12th 2020

Potential authors submit chapter proposals ready for review by the academic editor and our publishing review team.

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Approved chapters written in full and submitted

Deadline for full chapters: January 11th 2021

Once approved by the academic editor and publishing review team, chapters are written and submitted according to pre-agreed parameters

Full chapters peer reviewed

Review results due: April 1st 2021

Full chapter manuscripts are screened for plagiarism and undergo a Main Editor Peer Review. Results are sent to authors within 30 days of submission, with suggestions for rounds of revisions.

Book compiled, published and promoted

Expected publication date: May 31st 2021

All chapters are copy-checked and typesetted before being published. IntechOpen regularly submits its books to major databases for evaluation and coverage, including the Clarivate Analytics Book Citation Index in the Web of ScienceTM Core Collection. Other discipline-specific databases are also targeted, such as Web of Science's BIOSIS Previews.

About the editor

Kaneez Fatima Shad

University of Technology Sydney

Professor Kaneez Fatima Shad, a neuroscientist with a medical background, received PhD in 1994 from the Faculty of Medicine, UNSW, Australia, followed by a post-doc at the Allegheny University of Health Sciences, Philadelphia, USA. She taught Medical and Biological Sciences in various universities in Australia, USA, UAE, Bahrain, Pakistan, and Brunei. During this period, she was also engaged in doing research by getting local and international grants (total of over 2.3 million USD) and translating into products such as a rapid diagnostic test for stroke and other vascular disorders. She published over 60 articles in refereed journals, edited six books, and wrote 7 book chapters, presented at 85 international conferences, mentored thirty-four postgraduate students. Set up a company Shad Diagnostics for the development of cerebrovascular handheld diagnostic tool Stroke meter into a wearable.

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Book chapters authored 4

Books edited 6

Introducing your Author Service Manager

Mr. Josip Knapic

As an Author Service Manager my responsibilities include monitoring and facilitating all publishing activities for authors and editors. From chapter submission and review, to approval and revision, copy-editing and design, until final publication, I work closely with authors and editors to ensure a simple and easy publishing process. I maintain constant and effective communication with authors, editors and reviewers, which allows for a level of personal support that enables contributors to fully commit and concentrate on the chapters they are writing, editing, or reviewing. I assist authors in the preparation of their full chapter submissions and track important deadlines and ensure they are met. I help to coordinate internal processes such as linguistic review, and monitor the technical aspects of the process. As an ASM I am also involved in the acquisition of editors. Whether that be identifying an exceptional author and proposing an editorship collaboration, or contacting researchers who would like the opportunity to work with IntechOpen, I establish and help manage author and editor acquisition and contact.

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