Open access peer-reviewed Edited Volume


Syed Ali Raza Naqvi

Government College University


Muhammad Babar Imran

Punjab Institute of Nuclear Medicine

Giuliano Mariani

University of Pisa

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Derya İlem Özdemir

Ege University


Principles of radionuclide physics Radionuclide production Radiolabeling General localization mechanisms Single-photon-emitting radiopharmaceuticals Positron-emitting radiopharmaceuticals SPECT imaging PET Imaging Cancer imaging studies Metabolic disorder studies Quality control of radiopharmaceuticals Radioactive waste management

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About the book

The approach to radiopharmaceuticals development has expanded over the years. The first approach, most probably when Henri Alexandre Danlos and Eugene Bloch placed radium in contact with a tuberculosis skin lesion in 1901, was conducted in order to develop the use of radioactivity for medical use. In 1936, John H. Lawrence made the first clinical therapeutic application of an artificial radionuclide when he used phosphorus-32 to treat leukemia. These different activities with the passage of time were continuously translated into advanced theranostic techniques commonly known as Nuclear Medicine Techniques (NMT), which are mainly based on radiopharmaceuticals. More recently, radiopharmaceuticals are developed based on advanced knowledge in molecular biology techniques, which aim to better understand and define the target specificity, accuracy and binding sites for radiopharmaceuticals. As a result of these advances in NMT, deep seated and functional disorders related issues have been resolved. This book intends to provide the reader with a comprehensive overview on the radionuclide physics, development of radiopharmaceuticals, the role of radiopharmaceuticals in medical imaging and therapy of deep seated and functional disorders, advances in NMT with emphasis on target-based radiopharmaceuticals development, and prospects in the field of medical imaging.

Publishing process

Book initiated and editor appointed

Date completed: August 12th 2019

Applications to edit the book are assessed and a suitable editor is selected, at which point the process begins.

Chapter proposals submitted and reviewed

Deadline for chapter proposals: September 2nd 2019

Potential authors submit chapter proposals ready for review by the academic editor and our publishing review team.

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Approved chapters written in full and submitted

Deadline for full chapters: November 1st 2019

Once approved by the academic editor and publishing review team, chapters are written and submitted according to pre-agreed parameters

Full chapters peer reviewed

Review results due: January 20th 2020

Full chapter manuscripts are screened for plagiarism and undergo a Main Editor Peer Review. Results are sent to authors within 30 days of submission, with suggestions for rounds of revisions.

Book compiled, published and promoted

Expected publication date: March 20th 2020

All chapters are copy-checked and typesetted before being published. IntechOpen regularly submits its books to major databases for evaluation and coverage, including the Clarivate Analytics Book Citation Index in the Web of ScienceTM Core Collection. Other discipline-specific databases are also targeted, such as Web of Science's BIOSIS Previews.

About the editor

Syed Ali Raza Naqvi

Government College University

Since 2017, Dr. Syed Ali Raza Naqvi has been appointed as Associate Professor of Chemistry at Government College University, Faisalabad, Pakistan. He started his prior academic career as teaching assistant at the GC University, Lahore, and then he joined University of the Punjab for his PhD studies. In 2008, during his PhD studies he joined the Molecular Imaging research group of Prof. Stephen Mather in London, UK. After the completion of his PhD he joined Government College University as Assistant Professor of Chemistry in 2010. Dr. Naqvi’s research interests mainly focus on the development of radiopharmaceuticals, including both diagnostic and therapeutic applications, with emphasis on development of novel molecules for radionuclide-based diagnosis and therapy of different deep seated infections. He is the winner of many research grants and published over 70 articles in international peer-reviewed journals and has supervised almost 40 MS and PhD students.

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