About the book
In recent years, numerous studies have analyzed the role of Bioactive Glass (BG) as remineralizing additives in dental restorative composites. Bioactive glasses (BGs) are traditionally known to be able to bond to living bone and stimulate bone regeneration. The production of such materials allowed scientists to dramatically expand the versatility of oxide-based glass systems as well as their applications in biomedicine. BGs are used to regenerate bone by a mechanism which involves surface degradation, the release of ions such as calcium, soluble silica and phosphate and the precipitation of a biomimetic apatite surface layer on glass.
One major area of BG research is the incorporation of therapeutically active ions to broaden the application range of these materials. When developing such new compositions, in vitro cell culture studies are a key part of their characterisation. However, parameters of cell culture studies vary widely and, depending on the intended use of BG compositions, different layouts, cell types and assays need to be used. Also, surface coating on biomaterial implants remain a challenging task to researchers because of its simultaneous demand for various properties.