Open access peer-reviewed Edited Volume

Milk Protein - New Research Approaches

Narongsak Chaiyabutr

Chulalongkorn University

Prof. Narongsak Chaiyabutr is an appointed Fellow of the Royal Society of Thailand (FRST). Due to his contributions and international recognition, he received several awards including the Distinguished Researcher Award (Animal Production) at the 6th AAAP Congress (1992, Thailand), the National Outstanding Researcher Award (Agriculture and Biology) from the National Research Council of Thailand (1995), and the Distinguished Veterinarian Award from the Veterinary Medical Association of Thailand (1998).


Milk Milk Protein Mammary Gland Hormonal Modulation Genetic Factor Molecular Mechanism Nutritive Quality Lactation Breeding Milk Genomics Milk Proteomics Milk Coagulation

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About the book

Milk protein falls into the first category of milk production. An efficient milk protein production needs to improve in many aspects in different disciplines of knowledge to increase both quantity and quality of milk production. Understanding the details of mechanisms involved in milk protein synthesis is important not only for the fundamental mechanisms required for the control of protein synthesis, but also for the cellular and genetic mechanisms involved in the mammary cell for milk protein secretion. The growth and differentiation of the mammary gland are controlled by the multifactorial mammary cell functions, leading to the specific potential of milk protein production. An intricate combination of mechanisms of mammary cells and their products has contributed to the current broad knowledge of mammary gland physiology. Studies of the structure of milk protein genes, descriptions of specific receptors for growth factors, peptide and steroid hormones, and the clarification of hormone signaling pathways have made a considerable contribution to advances in understanding the mechanism of action of the hormonal regulation. An increasingly wide variety of biotechnological tools are now becoming available, and the genes transcribed in mammary tissues are now systematically being identified. However, despite the increase in knowledge about the genetics of dairy cows in recent decades, the genomic mechanisms influencing milk protein secretion relating to other milk compositions are to be investigated.

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About the editor

Narongsak Chaiyabutr

Chulalongkorn University

After graduating from Faculty of Veterinary Science, Chulalongkorn University, (D.V.M. degree in 1969), Prof. Narongsak Chaiyabutr joined Faculty of Veterinary Science, Chulalongkorn University, as an instructor in the Department of Physiology. He obtained his M.S. degree in Physiology from Mahidol University in 1971, and completed postgraduate training in Animal Physiology and Biochemistry under FAO fellowship at The Royal Veterinary and Agricultural University, Denmark (1971-1973). In 1978, he obtained a grant from Chulalongkorn University for his Ph.D study in the UK, and in 1980, he was awarded the Doctor of Philosophy degree from Glasgow University, Scotland, UK, for his thesis entitled "Control of Mammary Function During Pregnancy and Lactation in the Goat: Effects of Starvation". His study in the Nutrition Physiology discipline was conducted under the supervision of Prof. Dr. Malcolm Peaker and Dr. Anne Faulkner at the Hannah Research Institute. The focus of Prof. Chaiyabutr’s research is to study the field of animal physiology relating to agricultural science and biomedical science disciplines. He published more than 200 scientific papers in refereed journals, reviewed many research papers and reports, and has been invited to attend and give presentations at many international meetings and conferences in Asia and other parts of the world. As a result, Prof. Chaiyabutr gained professional recognition nationally and internationally as not only an animal scientist, but a medical scientist in general. He is very much responsible for the creation of new scientific works in the physiology discipline, not only in the area of animal science, but also related to medical science. With his contributions and international recognition, he received the Distinguished Researcher Award (Animal Production) at the 6th Asian-Australasian Association of Animal Production Society (AAAP) Congress (November 1992, Bangkok, Thailand). In 1995, he received the National Outstanding Researcher Award (Agriculture and Biology) from the National Research Council of Thailand. In 1998, he received the Distinguished Veterinarian Award (Academic discipline) from the Veterinary Medical Association of Thailand. Finally, in 2002, he received the Outstanding Research Award, Rachadapiseksompoj Fund, Chulalongkorn University. In the area of animal physiology research, including veterinary science and animal science, Prof. Chaiyabutr played a leading role in studying within the field of environmental physiology. He observed that the stress of hot environments lowered productive efficiency in livestock, both directly and indirectly in tropical conditions. The research findings lead to a better understanding of the mechanisms for thermo-regulation in domestic animals. The scope of this work contributed to advancing knowledge of the animal physiology, not only for the benefit in the development of livestock production in the country, but also for other tropical countries. Prof. Chaiyabutr has also been contributing to the scientific work in dairy science. His research study involved the physiology of the mammary gland and milk secretion in both dairy goat and crossbred dairy cattle in the tropics. He observed that the low milk yield and short lactation period of either pure exotic or crossbred dairy cattle was a major problem for the Thai dairy practices. The rapid decrease in milk yield after peak lactation in dairy cattle has long been a biological conundrum for mammary biologists, as well as a cause of considerable lost income for the dairy farmers. Several kinds of researches have been attempted to try to improve dairy productivity, and there is still a need to identify the type of crossbred cattle that is the most suitable for the tropics. Furthermore, Prof. Chaiyabutr is responsible for the creation of physiology knowledge involving medical science. The physiological field experience led him to do research work related to medical science explaining that acute renal failure in a patient with snake bite (particularly Russell’s viper snake) is a result of a medical problem. In collaboration with the Faculty of Medicine, CU, a study on the effect of Russell’s viper venom on kidney function in experimental animals was started in 1982. From this study, it was learned that acute renal failure is an important complication during envenomation by Russell’s viper. Prof. Chaiyabutr's pioneering work in physiological science is reflected in his research and basic science contributions to this society.

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