Open access peer-reviewed Edited Volume

Biopharmaceuticals - Fabrication of Smart Architectures as Drug Cargoes

Gul Shahnaz

Quaid-i-Azam University


Novel drug delivery systems Pharmacokinetic behavior Stimuli responsive Multi-functionalization Polymer drug conjugates Dendrimers Nanocrystals Polymerosomes Liposomes Micelles Niosomes Nucleic acid mediated nanostructures Immunotherapeutic technology Biomimics biotempltes tunable membrane properties Bio-Metal organic frameworks (Bio-MOFs)

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About the book

Biopharmaceutical therapeutics comprise of heterogeneous structurally complex drug molecules for potential therapy and diagnosis in diverse clinical settings such as infectious diseases, cancer, metabolic irregularities, and immunizations, etc. Structural complexity and heterogeneity of therapeutic modalities is often required for high specificity, potency, efficacy and safety. However, structural complexity and heterogeneity of these biopharmaceuticals is a major challenge to formulate and deliver intact to their extracellular and intracellular target sites. Biopharmaceuticals - Fabrication of Smart Architectures as Drug Cargoes hopes to highlight recent advances in formulation and delivery strategies from plain drug reformulation and modified release technologies to innovative platforms that hold enormous potential for the effective delivery of heterogeneous drugs. Technologies such as micro- and nanocargoes, stimuli-responsive systems, macromolecular conjugation and microfabricated systems have become more mainstream over recent years. In addition, surface engineered multifunctional polymeric carrier’s technology for diverse range of therapeutic modalities is precisely designed to improve penetration, absorption, and retention of drugs in hard-to-penetrate tissues. Other interesting carrier systems including lipid based vesicles, carbon nanostructures, metallic nanocarriers, immunotherapeutic agents, nucleic acid based structures and biomimics have shown enormous potential not only for targeted delivery of drug but also for diagnostic applications.

Publishing process

Book initiated and editor appointed

Date completed: September 2nd 2019

Applications to edit the book are assessed and a suitable editor is selected, at which point the process begins.

Chapter proposals submitted and reviewed

Deadline Extended: Open for Submissions

Potential authors submit chapter proposals ready for review by the academic editor and our publishing review team.

Approved chapters written in full and submitted

Deadline for full chapters: November 22nd 2019

Once approved by the academic editor and publishing review team, chapters are written and submitted according to pre-agreed parameters

Full chapters peer reviewed

Review results due: February 10th 2020

Full chapter manuscripts are screened for plagiarism and undergo a Main Editor Peer Review. Results are sent to authors within 30 days of submission, with suggestions for rounds of revisions.

Book compiled, published and promoted

Expected publication date: April 10th 2020

All chapters are copy-checked and typesetted before being published. IntechOpen regularly submits its books to major databases for evaluation and coverage, including the Clarivate Analytics Book Citation Index in the Web of ScienceTM Core Collection. Other discipline-specific databases are also targeted, such as Web of Science's BIOSIS Previews.

About the editor

Gul Shahnaz

Quaid-i-Azam University

Dr. Gul Shahnaz is serving as assistant professor at Department of Pharmacy, Quaid-i-Azam University, Islamabad, Pakistan. She has more than a decade of professional expertise in pharmaceutical and biomedical sciences. Her particular expertise in leading and executing projects relate to biopharmaceutical and biochemical designing, formulation of multifunctional polymeric excipients, lipid based nano-vesicles, organometallic nanocargoes; and studies in cancer, wound healing, several infectious diseases applications. Her expertise and professional development has grown through work with academic and healthcare institutions, including Prof. Dr. Andreas Bernkop-Schnürch, university of Innsbruck, Austria, University of Nebraska Medical Center and Ohio State University, USA. She has authored numerous peer reviewed articles (impact factor ~140 and citations= 789). She has earned PhD in Pharmaceutical Technology, Master of Science in Pharmaceutics, as well as a Bachelor of Science in Pharmacy.

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