About the book
Hepatocellular carcinoma (HCC) is among the most prevalent tumor types worldwide. Diagnosis is late because early HCC is mostly asymptomatic. The mortality rate is high even with current treatments. HCC can develop from multiple etiologies (e.g., hepatitis B and C as well as NASH), but the pathogenesis of this tumor type is poorly understood, as are the mechanisms of disease that are shared among its’ different etiologies.
This book will provide chapters that will attempt to identify common denominators of HCC pathogenesis at the molecular, cellular, and immunologic levels prior to tumor development and during tumor progression. This will define critical targets for new prognostic assays and therapeutic approaches that would be valuable prior to and after a cancer diagnosis.