Open access peer-reviewed Edited Volume

Bacterial Virulence

Mona Shaaban

Mansoura University


Abdelaziz Elgaml

Mansoura University


Virulence factors Adhesion Motility Biofilm Exotoxins LPS Quorum sensing Exoenzymes Proteases Hemolysin Pigment formation Antivirulent

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About the book

The pathogenicity of microorganisms are directly associated with multiple virulence factors secreted by microbial community. Bacterial adhesion to the host through pili is the first virulent attribute of microbial infection with expression of cell surface components to invade the host cells. Bacteria can also secret multiple virulence factors, such as degrading enzymes such as proteases, haemolysin, and elastase, these enzymes enhance bacterial dissemination. Furthermore, the accumulated extracellular polysaccharides, assembly of biofilm layers and low penetration of antimicrobial agents is another important virulent behavior. This book will review the virulence attributes of the most important pathogenic bacteria including Pseudomonas Sp., Vibrio Sp., Enterobacteriaceae, Staphylococcus aureus, Streptococcus and Enterococcus Sp. The canonical pathogenic mechanisms will be elucidated and how each virulence factor is related to microbial infection and invasion. Additionally, the recent efforts to inhibit the release of these virulence factors with the goal of designing novel antivirulence agents will be explained.

Publishing process

Book initiated and editor appointed

Date completed: August 6th 2019

Applications to edit the book are assessed and a suitable editor is selected, at which point the process begins.

Chapter proposals submitted and reviewed

Deadline Extended: Open for Submissions

Potential authors submit chapter proposals ready for review by the academic editor and our publishing review team.

Approved chapters written in full and submitted

Deadline for full chapters: October 26th 2019

Once approved by the academic editor and publishing review team, chapters are written and submitted according to pre-agreed parameters

Full chapters peer reviewed

Review results due: January 14th 2020

Full chapter manuscripts are screened for plagiarism and undergo a Main Editor Peer Review. Results are sent to authors within 30 days of submission, with suggestions for rounds of revisions.

Book compiled, published and promoted

Expected publication date: March 14th 2020

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About the editor

Mona Shaaban

Mansoura University

Dr. Shaaban is an Associate Professor of Microbiology and Immunology, Faculty of Pharmacy, Mansoura University, Mansoura, Egypt. She received her Ph.D. in Mansoura University, Egypt through a joint scholarship with University of Wisconsin Madison, USA.  Moreover, Dr. Shaaban got her MSc degrees in Microbiology and Immunology Department, Faculty of Pharmacy, Mansoura University, Mansoura, Egypt. She has 40 publications in international Journals and is serving as a reviewer at impacted journals as PLOS one, scientific reports, Frontiers in Microbiology and Microbiology Research International and other Journals. Dr. Shaaban main research interests are quorum sensing and microbial virulence factors, quorum sensing inhibition as an antipathogenic approach to eliminate bacterial virulence and toxins, microbial resistance and development of nanoparticles to compete for bacterial resistance and virulence.

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As an Author Service Manager my responsibilities include monitoring and facilitating all publishing activities for authors and editors. From chapter submission and review, to approval and revision, copyediting and design, until final publication, I work closely with authors and editors to ensure a simple and easy publishing process. I maintain constant and effective communication with authors, editors and reviewers, which allows for a level of personal support that enables contributors to fully commit and concentrate on the chapters they are writing, editing, or reviewing. I assist authors in the preparation of their full chapter submissions and track important deadlines and ensure they are met. I help to coordinate internal processes such as linguistic review, and monitor the technical aspects of the process. As an ASM I am also involved in the acquisition of editors. Whether that be identifying an exceptional author and proposing an editorship collaboration, or contacting researchers who would like the opportunity to work with IntechOpen, I establish and help manage author and editor acquisition and contact.

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