Open access peer-reviewed Edited Volume

Cerebral Circulation - Updates on Models, Diagnostics and Treatments of Related Diseases

Alba Scerrati

University of Ferrara

Dr. Sceratti completed her neurosurgical residency in 2017 at the Catholic University of Rome, Italy. Her main scientific interests include skull base surgery, neurooncology, and neurovascular surgery. She is a member of SINCH (Società Italiana di Neurochirurgia) and EANS (European Association of Neurological Surgeons).


Luca Ricciardi

Sapienza University of Rome

Dr. Ricciardi completed his fellowship in spinal deformities at the Catholic University of Rome, Italy in 2017, and a research fellowship at Mayo Clinic, US in 2018. In 2021, he was invited as Guest Editor for the Journal of Neurosurgical Sciences, and as Invited Editor on Frontiers in Neurology. Dr. Ricciardi has been nominated as co-chairman and President of the Scientific Committee at SPINE20, the World Congress on Spine Disorders in Rome, Italy.

Flavia Dones

Arcispedale Sant'Anna

Dr. Dones completed her neurosurgical residency in 2017 at the University of Naples "Federico II", Italy. Her main interests are neurovascular and neurooncology surgery.


Glymphatic System Cerebral Blood Flow Vascular Permeability MR Thermometry Fluid Shear Stress Targeted Bypass Strategy Cerebral Proliferative Angiopathy Cerebral Hemorrhage BBB Dysregulation Venous Thrombosis Meniere's Disease Idiopathic Intracranial Hypertension

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About the book

The term "cerebral circulation" contains a large number of concepts which intertwine with each other. Arteries, veins and microcirculation constitute the substrate for developing different kinds of diseases.

New anatomo-physiological models for microcirculation are being developed in order to establish possible relationships with several neurodegenerative diseases. Blood-brain barrier and neurovascular unit models are proposed for studying mechanisms of neurodegeneration. Diagnostic imaging tools are continuously evolving in order to detect every anatomic, but also functional detail. Combined computational flow dynamics or silent magnetic resonance angiography are just a few of the newly developed imaging techniques. The frontiers of treatment of ischemic or hemorrhagic stroke are expanding, in particular for the treatment of the secondary damages such as delayed cerebral ischemia. Finally, the venous system is attracting more and more interest. Several central nervous system disorders, such as Ménière’s disease, idiopathic intracranial hypertension, multiple sclerosis and transient monocular blindness have been associated with an impaired venous outflow.

The aim of the present book is to provide the reader with a comprehensive overview of the current state-of-the-art on cerebral circulation and new frontiers on models, diagnostics and treatments of related diseases.

Publishing process

Book initiated and editor appointed

Date completed: September 3rd 2021

Applications to edit the book are assessed and a suitable editor is selected, at which point the process begins.

Chapter proposals submitted and reviewed

Deadline for chapter proposals: October 1st 2021

Potential authors submit chapter proposals ready for review by the academic editor and our publishing review team.

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Approved chapters written in full and submitted

Deadline for full chapters: November 30th 2021

Once approved by the academic editor and publishing review team, chapters are written and submitted according to pre-agreed parameters

Full chapters peer reviewed

Review results due: February 18th 2022

Full chapter manuscripts are screened for plagiarism and undergo a Main Editor Peer Review. Results are sent to authors within 30 days of submission, with suggestions for rounds of revisions.

Book compiled, published and promoted

Expected publication date: April 19th 2022

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About the editor

Alba Scerrati

University of Ferrara

Dr. Alba Scerrati was born in Rome, where she lived until 2017. She graduated from medical school in 2010 and completed her neurosurgical residency in 2017 at the Catholic University of Rome, Policlinico Gemelli. Since 2019 she is an Assistant Professor of Neurosurgery at the University of Ferrara where she also works as a neurosurgeon. Dr. Scerrati’s main scientific interests are in skull base surgery, neuroncology and neurovascular surgery. She is the author and co-author of more than 50 indexed publications (

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