About the book
Gestational diabetes mellitus is defined as diabetes diagnosed in the second or third trimester of pregnancy, with no evidence of pre-existing type 1 or type 2 diabetes. Although gestational diabetes mellitus normally disappears after delivery, this pathological condition may have long-term medical consequences for both mother and offspring. In accordance, increased risk of miscarriage, macrosomia, complications around delivery and stillbirth have been clearly connected with diabetes developed during pregnancy. Although much knowledge has been acquired regarding prevention, diagnosis, implications, and management of gestational diabetes mellitus, the exact mechanisms of gestational diabetes mellitus development are still under investigation. In that way, we can recognize recent efforts in deeper understanding of the adverse genetic background and the epigenetic modifications linked to nutritional and environmental factors in affecting hyperglycemia of pregnant woman and future fetal metabolism. Pharmacological and non-pharmacological treatment of gestational diabetes are aimed to maintain euglycemia with regular glucose monitoring, dietary modifications, life style changes, exercise program, and appropriate pharmacotherapy.
Therefore, the aims of this book would be to clarify recent advances in epidemiology, pathophysiology, diagnosis, treatment and medical consequences of gestational diabetes mellitus.