About the book
Muscular dystrophy represents a group of more than 30 inherited diseases that are characterized by muscle weakness and loss of muscle mass over time caused by genetic alterations. Even though more than 30 years have passed since the discovery of the first protein involved in a type of muscular dystrophy, there is no cure for these conditions yet.
This book aims to provide an overview of the recent advances in the muscular dystrophy field addressing the cellular and molecular basis of muscular dystrophy, signaling pathways involved in skeletal muscle remodeling, miRNA profiling, serum, inflammatory and regenerative biomarkers. This book will discuss the currently available and innovative molecular techniques used for muscular dystrophy diagnosis (muscle biopsy, multiplex ligation-dependent probe amplification (MLPA), CGH-array, next-generation sequencing) as well as newest therapeutic approaches for different types of muscular dystrophies.
This book will be of great interest to students, Ph.D. students in various medical sciences, researchers in the muscular dystrophy field and medical doctors.