Open access peer-reviewed Edited Volume

Systems Biology - The Third Millennium Biology Challenge

Nicola Bernabò

University of Teramo


Systems biology Mathematical models Computational models Omics High throughput technologies Big data Biological networks Personalized medicine Molecular biology Cell biochemistry Biological pathways Cell communication

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About the book

Third millennium biology and medicine are faced with new and important challenges. On the one hand, the development of new high throughput technologies, the so-called omics has led to an amazing increase in data availability for scientists, that require the implementation of interpretative models, while on the other hand, the need of an even more patient-specific approach (personalized medicine) has become a limiting factor. To overcome this unprecedented condition, a new way to think about living systems has been developed, and it is based on computational and mathematical analysis and modelling of biological entities, from molecules and cells to tissues, organs, and ultimately whole organisms - systems biology. Systems biology is, by definition, a very multidisciplinary branch of science, involving mathematicians, physicists, computer scientists, as well as biologists, doctors, and health professionals. It focuses on the study of biological complex systems adopting a new holistic approach in which living beings are analysed with a bottom-up perspective. This book intends to provide the reader with a comprehensive overview of the current state-of-the-art of this very fascinating and promising science, with special focus on cutting edge systems biology methodologies applied in molecular biology, biochemistry, and medicine.

Publishing process

Book initiated and editor appointed

Date completed: October 28th 2019

Applications to edit the book are assessed and a suitable editor is selected, at which point the process begins.

Chapter proposals submitted and reviewed

Deadline Extended: Open for Submissions

Potential authors submit chapter proposals ready for review by the academic editor and our publishing review team.

Approved chapters written in full and submitted

Deadline for full chapters: January 17th 2020

Once approved by the academic editor and publishing review team, chapters are written and submitted according to pre-agreed parameters

Full chapters peer reviewed

Review results due: April 6th 2020

Full chapter manuscripts are screened for plagiarism and undergo a Main Editor Peer Review. Results are sent to authors within 30 days of submission, with suggestions for rounds of revisions.

Book compiled, published and promoted

Expected publication date: June 5th 2020

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About the editor

Nicola Bernabò

University of Teramo

Prof. Nicola Bernabò is an Associate Professor of Veterinary Physiology at Faculty of Veterinary Medicine, University of Teramo, Italy. He received the degree in veterinary medicine from University of Pisa (1999), the Master degree in biotechnology of reproduction from University of Teramo (2002), and PhD degree in endocrinology of domestic animals from University of Bologna (2004). His research interests include endocrinology of reproduction, biochemistry of sperm capacitation, and systems biology. In particular, his work is focused on development of computational models representing the complex biochemical events that occur during the acquisition of fertilizing ability by male gametes either in domestic animals and humans. Prof. Bernabò is author of more than sixty works published in international peer-reviewed journals, conference proceedings, as well as book chapters, and he has been awarded with national and international prizes for his research activity.

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Book chapters authored 3

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As an Author Service Manager my responsibilities include monitoring and facilitating all publishing activities for authors and editors. From chapter submission and review, to approval and revision, copyediting and design, until final publication, I work closely with authors and editors to ensure a simple and easy publishing process. I maintain constant and effective communication with authors, editors and reviewers, which allows for a level of personal support that enables contributors to fully commit and concentrate on the chapters they are writing, editing, or reviewing. I assist authors in the preparation of their full chapter submissions and track important deadlines and ensure they are met. I help to coordinate internal processes such as linguistic review, and monitor the technical aspects of the process. As an ASM I am also involved in the acquisition of editors. Whether that be identifying an exceptional author and proposing an editorship collaboration, or contacting researchers who would like the opportunity to work with IntechOpen, I establish and help manage author and editor acquisition and contact.

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