About the book
Third millennium biology and medicine are faced with new and important challenges. On the one hand, the development of new high throughput technologies, the so-called omics has led to an amazing increase in data availability for scientists, that require the implementation of interpretative models, while on the other hand, the need of an even more patient-specific approach (personalized medicine) has become a limiting factor. To overcome this unprecedented condition, a new way to think about living systems has been developed, and it is based on computational and mathematical analysis and modelling of biological entities, from molecules and cells to tissues, organs, and ultimately whole organisms - systems biology. Systems biology is, by definition, a very multidisciplinary branch of science, involving mathematicians, physicists, computer scientists, as well as biologists, doctors, and health professionals. It focuses on the study of biological complex systems adopting a new holistic approach in which living beings are analysed with a bottom-up perspective. This book intends to provide the reader with a comprehensive overview of the current state-of-the-art of this very fascinating and promising science, with special focus on cutting edge systems biology methodologies applied in molecular biology, biochemistry, and medicine.