Open access peer-reviewed Edited Volume

Pharmacogenetics

Islam Khalil

Misr University for Science and Technology

Dr. Islam Khalil worked as a postdoctoral research fellow in an American university in Cairo, Zewail City for Science and Technology, and Brigham and Women's Hospital, Harvard Medical School (Fulbright visiting scholar). His research is focused on designing, developing, and evaluating nanoscale carriers and scaffolds for various biomedical applications such as therapeutics and tissue regeneration.

Covering

Nanomedicine Personalized Medicine Pharmacogenomics Pharmacotyping Pharmacogenetics Pharmacokinetics Pharmacodynamic Gene Genome Drug Response Drug Development Research and Development

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About the book

Pharmacogenetics is the effect of one gene variation on a single drug response while Pharmacogenomics is the effect of the genome (all the genes) on drug responses. Although the field of pharmacogenetics was established in the 1950s, clinical testing for constitutional pharmacogenetic variants implicated in interindividual drug response variability has only recently become available to help clinicians guide pharmacotherapy. In recent years, the convergence of advances in pharmacogenetics with rapid developments in human genomics has resulted in the evolution of pharmacogenetics into pharmacogenomics and led to increasing enthusiasm for the 'translation' of this evolving discipline into clinical practice. On the other hand, the developments of the nanotechnology field generated new potentials of therapeutic nanocarriers in the field of personalized medicine. Although the nanomaterials are of the same dimensions as many cellular types of machinery, their interaction with cells, tissues, and organs of the body are not well understood. This in turn forms the rationale for a comprehensive study of these nanoplatforms in various disease models in terms of their toxicity, pharmacokinetics, pharmacodynamics, and pharmacogenetics. Such a study will significantly aid in our quest in translating its application from bench to bedside.

Publishing process

Book initiated and editor appointed

Date completed: October 27th 2020

Applications to edit the book are assessed and a suitable editor is selected, at which point the process begins.

Chapter proposals submitted and reviewed

Deadline Extended: Open for Submissions

Potential authors submit chapter proposals ready for review by the academic editor and our publishing review team.

Approved chapters written in full and submitted

Deadline for full chapters: January 23rd 2021

Once approved by the academic editor and publishing review team, chapters are written and submitted according to pre-agreed parameters

Full chapters peer reviewed

Review results due: April 13th 2021

Full chapter manuscripts are screened for plagiarism and undergo a Main Editor Peer Review. Results are sent to authors within 30 days of submission, with suggestions for rounds of revisions.

Book compiled, published and promoted

Expected publication date: June 12th 2021

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About the editor

Islam Khalil

Misr University for Science and Technology

Islam Khalil is an associate professor of pharmaceutics at the College of Pharmacy, Misr University for Science and Technology (Egypt). He received his B.Sc. in pharmaceutical sciences from Misr University for Science and Technology in 2003, his M.Sc. in 2009, and Ph.D. in 2013 in pharmaceutics from Faculty of Pharmacy, Cairo University (Egypt). He worked as a postdoctoral research fellow in an American university in Cairo, Zewail City for Science and Technology, and Brigham and Women's Hospital, Harvard Medical School (Fulbright visiting scholar). He also worked as a consultant in the pharmaceutical industry and bio-equivalent centers. His research is focused on designing, developing, and evaluating of nanoscale carriers and scaffolds for various biomedical applications such as therapeutics and tissue regeneration.

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Book chapters authored 1

Books edited 1

Introducing your Author Service Manager

Ms. Romina Rovan

As an Author Service Manager my responsibilities include monitoring and facilitating all publishing activities for authors and editors. From chapter submission and review, to approval and revision, copyediting and design, until final publication, I work closely with authors and editors to ensure a simple and easy publishing process. I maintain constant and effective communication with authors, editors and reviewers, which allows for a level of personal support that enables contributors to fully commit and concentrate on the chapters they are writing, editing, or reviewing. I assist authors in the preparation of their full chapter submissions and track important deadlines and ensure they are met. I help to coordinate internal processes such as linguistic review, and monitor the technical aspects of the process. As an ASM I am also involved in the acquisition of editors. Whether that be identifying an exceptional author and proposing an editorship collaboration, or contacting researchers who would like the opportunity to work with IntechOpen, I establish and help manage author and editor acquisition and contact.

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