Open access peer-reviewed Edited Volume

Autism - Heterogeneity Etiological Core and Outcome

Marwa Saleh

Ain Shams University


Single Gene Neurological Comorbidities Grey and White Matter Frontal and Temporal Lobes Dietary Patterns Pre- and Post-Natal Factors Brain Overgrowth Long Distance Underconnectivity Cognitive Impairment Childhood Apraxia of Speech Socioeconomic Factors Degree of Intelligence

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About the book

Autism presents a heterogenous pool of implicated etiological factors, clinical deviations and comorbidities. The core symptoms present the only common block in the human building of autism; with defective communicative development and restrictive behavior. Therefore no single theory can describe autism. It is a multifactorial neurodevelopmental disorder or disorders. Etiology covers genetic, neurobiological, and environmental factors. Due to the association of comorbidities, the clinical picture is skewed toward the prevalent symptoms. Comorbidities include cognitive impairment, attention deficit-hyperactivity disorder, apraxia, and sensory integration disorder. Heterogeneity exists in brain findings, ranging from structural changes in frontal and anterior temporal lobes, caudate, cerebellum, grey and white matter and functional long-distance underconnectivity with local over-connectivity. Good language and intellectual abilities are favorable prognostic factors. Review of the researched underlying and presenting factors could help clarify the pathway toward incorporating the autism individuals into the environment and potentially directing some of them out of the autism spectrum.

Publishing process

Book initiated and editor appointed

Date completed: May 22nd 2020

Applications to edit the book are assessed and a suitable editor is selected, at which point the process begins.

Chapter proposals submitted and reviewed

Deadline for chapter proposals: June 12th 2020

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Approved chapters written in full and submitted

Deadline for full chapters: August 11th 2020

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Full chapters peer reviewed

Review results due: October 30th 2020

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Expected publication date: December 29th 2020

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About the editor

Marwa Saleh

Ain Shams University

Professor Marwa Mahmoud Saleh is a doctor of medicine and currently works in the unit of Phoniatrics, Department of Otolaryngology, Ain Shams University in Cairo, Egypt. She got her doctoral degree in 1991 and her doctoral thesis was accomplished in the University of Iowa, United States. Her publications covered a multitude of topics as videokymography, cochlear implants, stuttering, and dysphagia. She has lectured Egyptian phonology for many years. Her recent research interest is joint attention in autism.

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Book chapters authored 2

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