About the book
Autism presents a heterogenous pool of implicated etiological factors, clinical deviations and comorbidities. The core symptoms present the only common block in the human building of autism; with defective communicative development and restrictive behavior. Therefore no single theory can describe autism. It is a multifactorial neurodevelopmental disorder or disorders. Etiology covers genetic, neurobiological, and environmental factors. Due to the association of comorbidities, the clinical picture is skewed toward the prevalent symptoms. Comorbidities include cognitive impairment, attention deficit-hyperactivity disorder, apraxia, and sensory integration disorder. Heterogeneity exists in brain findings, ranging from structural changes in frontal and anterior temporal lobes, caudate, cerebellum, grey and white matter and functional long-distance underconnectivity with local over-connectivity. Good language and intellectual abilities are favorable prognostic factors. Review of the researched underlying and presenting factors could help clarify the pathway toward incorporating the autism individuals into the environment and potentially directing some of them out of the autism spectrum.