About the book
Recent research has established the mesentery to be a far more than simple organ. With the inclusion of mesentery, the total number of human organs has increased. The mesentery is not just a fatty covering protection for the intestines, on the contrary, visceral adipose tissue is an active multifunctional metabolic organ involved in lipid storage and immunological and endocrine activity. Bowel inflammation penetrates the surrounding adipose tissue along the mesentery. Mesenteric fat serves as a barrier to inflammation and controls immune responses to the translocation of gut bacteria. The Peyer's patches (PP) and mesenteric lymph nodes (MLN) are structural components of the gut-associated lymphoid tissues and contribute to the induction of immune responses toward infection in the gastrointestinal tract.
The abdominal mesenteries are important peritoneal structures that give rise to a wide spectrum of abnormalities, including solid mesenteric masses. Despite similarities in appearance, solid masses in the mesentery may have diverse etiologies. The possible etiologic causes encompass a wide spectrum of underlying pathologies including infectious, inflammatory, and neoplastic processes, the vascular lesions have a greater frequency in older people and in children there are more prevalent congenital in nature. Unfortunately, the clinical and imaging findings are often non-specific and may overlap. While metastases are the most common cause of solid masses in the mesentery, other less common conditions are also important diagnostic considerations. The most common are four pathologic entities (sclerosing mesenteritis, carcinoid tumors, desmoids tumors and gastrointestinal stromal tumors) that may be manifested on abdominal imaging examinations by one or more mesenteric masses. These four pathologic lesions help to present a systematic approach to the radiographic characterization of solid mesenteric masses based on the morphology of the lesions, and distant findings on various abdominal imaging examinations.
This book intends to provide the reader with a discussion about possible impact of the mesentery on absorption, distribution, metabolism, and excretion.