About the book
This book will focus on sex hormones. Steroidogenesis will be reviewed in-depth along with disorders related to steroidogenesis. Included in with steroidogenesis will be clinical applications and disorders related to aberrant sex steroid hormone production. This includes congenital adrenal hyperplasia among other rarer disorders. Sex steroid hormone structure and function will be reviewed with a focus on estrogen, progesterone and testosterone. This will discuss not only the structure of molecules but how the structural differences confer biologic differences in activity in vivo. Gonadal and adrenal steroidogenesis will be reviewed with a chapter dedicated to unique sex steroid production in the adrenal gland. Role of sex steroid hormones outside of reproductive health will be explored including (but not limited to): mental health, cardiovascular health, and immunity. Finally, the pharmacology of sex hormones will be reviewed including options and clinical applications for hormone replacement therapy. Together, this will provide a comprehensive review of both pharmacologic, clinical and biochemistry of sex steroid hormones. We envision this chapter will be an in-depth look at sex hormones starting with production, including clinical applications and reviewing pharmacologic uses.