Open access peer-reviewed Edited Volume

Neuroendocrine Neoplasms - Diagnostics and Treatment

Pasquale Cianci

University of Foggia, Italy

Researcher in general surgery, Ph.D. and Fellow of the ACS, contract Professor at the University of Foggia. Associate Editor at Frontiers in Surgical Oncology, BMC Surgery, Annals of Medicine, and InTech Open Book Series. Reviewer for many major surgery journals.


Enrico Restini

ASL BAT - Department of Surgery and Traumatology

A pioneer in minimally invasive surgery with particular application to laparoscopy and robotics. Director of the General surgery unit of the Lorenzo Bonomo hospital - Andria (Italy), Head of the Surgery and Traumatology Department of the ASL-BAT. He holds the corporate license to use the Da Vinci Xi, Flex Robotics system, and Cyberknife.


Genetic Risks Multiple Endocrine Neoplasia Epidemiology Clinical Aspects Classification Biomarkers Carcinoid Syndrome Immune Factors Chemotherapy CT MRI F-FDG

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About the book

Neuroendocrine tumors (NETs) are rare tumors derived from the neuroendocrine cell system and are more commonly found in the gastrointestinal (GI) tract, as well as in other locations. They are relatively rare, accounting for 2% of all malignancy cases in the United States. In recent years their incidence has been increasing also as a result of the improved instrumental investigations available. Most patients are asymptomatic and these neoplasms are detected during routine examinations. Clinical presentation depends on the organ being involved and the hormone being secreted. Several biochemical tests are developed to help with the diagnosis of NETs including 5-hydroxyindoleacetic acid (5-HIAA) and chromogranin A (CgA). The improved diagnostic techniques allow today the earlier recognition of these tumors. The natural history, diagnosis, and management of these tumors may not be fully understood. Treatment involves a surgical approach, for both primary and metastatic lesions, as well as medical management for symptom management and disease progression. This book will aim to review the current clinical knowledge regarding the diagnosis, treatment, and prognosis of these fascinating neoplasms and the associated hormonal syndromes.

Publishing process

Book initiated and editor appointed

Date completed: April 21st 2022

Applications to edit the book are assessed and a suitable editor is selected, at which point the process begins.

Chapter proposals submitted and reviewed

Deadline Extended: Open for Submissions

Potential authors submit chapter proposals ready for review by the academic editor and our publishing review team.

Approved chapters written in full and submitted

Deadline for full chapters: July 18th 2022

Once approved by the academic editor and publishing review team, chapters are written and submitted according to pre-agreed parameters

Full chapters peer reviewed

Review results due: October 6th 2022

Full chapter manuscripts are screened for plagiarism and undergo a Main Editor Peer Review. Results are sent to authors within 30 days of submission, with suggestions for rounds of revisions.

Book compiled, published and promoted

Expected publication date: December 5th 2022

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About the editor

Pasquale Cianci

General Surgeon at 'Lorenzo Bonomo” Hospital-Department of Surgery and Traumatology-ASL BAT-Andria-Puglia (Italy), and Ph.D. at the Department of Medical and Surgical Sciences, University of Foggia (Italy), Fellow of American College of Surgeons (FACS). Contract Professor in General and Emergency Surgery, Gastroenterology and Human Physiology, Faculty of Medicine - Nursing Science and Physiotherapy Courses. Professor in surgical anatomy at the specialty school in general surgery. Contract Professor of I Level Masters: Intestinal stoma care nurse, Operating room nurse and Emergency medicine and critical area. Member of some of the most important Italian Scientific Surgical Societies: EAES, SICE, ACOI, SPIGC, SIUCP, ACS. Author of 70 national and international scientific papers, books and book chapters which are well appreciated in the health community. Editorial Board member of Frontiers in Surgical Oncology, BMC Surgery, Annals of Medicine, WJSP, Asian Journal of Research and Reports in Endocrinology, IntechOpen Edition. Reviewer of major international scientific journals such as Medicina, the Turkish Journal of Gastroenterology, Medical Principles and Practice, IntechOpen Edition, World Journal of Surgical Procedures, Oxford Medical Case Reports, BMJ Case Reports, Austin Pancreat Disord, World Journal of Gastroenterology, Case Studies in Surgery, World Journal of Surgical Oncology, Journal of Cancer and Tumor International, Journal of Basic and Applied Research International, International Journal of Medical and Pharmaceutical Case Reports, British Journal of Medicine and Medical Research, Faculty and Speaker at numerous national and international Surgical Congresses. Special interest in laparoscopic surgery, robotic surgery, endocrine surgery and coloproctology.

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Book chapters authored 4

Books edited 2

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