About the book
Neuroendocrine tumors (NETs) are rare tumors derived from the neuroendocrine cell system and are more commonly found in the gastrointestinal (GI) tract, as well as in other locations. They are relatively rare, accounting for 2% of all malignancy cases in the United States. In recent years their incidence has been increasing also as a result of the improved instrumental investigations available. Most patients are asymptomatic and these neoplasms are detected during routine examinations. Clinical presentation depends on the organ being involved and the hormone being secreted. Several biochemical tests are developed to help with the diagnosis of NETs including 5-hydroxyindoleacetic acid (5-HIAA) and chromogranin A (CgA). The improved diagnostic techniques allow today the earlier recognition of these tumors. The natural history, diagnosis, and management of these tumors may not be fully understood. Treatment involves a surgical approach, for both primary and metastatic lesions, as well as medical management for symptom management and disease progression. This book will aim to review the current clinical knowledge regarding the diagnosis, treatment, and prognosis of these fascinating neoplasms and the associated hormonal syndromes.
