Open access peer-reviewed Edited Volume

Physiology and Disorders of Adipose Tissue

Hassan M. Heshmati

Endocrinology Metabolism Consulting, LLC

A clinical researcher in Endocrinology and Metabolism with 44 years of experience in Academia and Pharmaceutical Companies and 267 presentations and publications.


Adipose Tissue Anatomy Subcutaneous Fat Visceral Fat Nerves Hormones Nerves Hormones Adipokines Leptin Endocrine-Disrupting Chemicals Obesity

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About the book

Adipose tissue is an important organ located beneath the skin (subcutaneous fat), around internal organs (visceral fat), and in the bone marrow. There are three types of adipose tissue, white adipose tissue (the predominant type), brown adipose tissue, and beige adipose tissue (new classification). The adipose tissue contains adipocytes (white, brown, and beige), connective tissue (fibroblasts), nerve tissue, vascular cells, and immune cells (macrophages). The white adipose tissue plays a vital role in the survival of humans. It is involved in heat insulation, mechanical protection (cushion), and storage of excess energy as triglycerides. The white adipose tissue is a highly metabolic and endocrine organ. It is involved in the production of several factors called adipokines (e.g., leptin, adiponectin, resistin, and adipsin) which act at both local (autocrine, paracrine) and systemic (endocrine) levels, affecting energy homeostasis, insulin sensitivity, and neuroendocrine, cardiovascular, and immune functions. The brown adipose tissue is involved in thermoregulation. It transfers energy from food into heat. The exact role of beige adipose tissue has yet to be determined. Aging is commonly associated with an increase in white adipose tissue and a decrease in brown adipose tissue. Disorders of white adipose tissue include accumulation of lipophilic endocrine-disrupting chemicals capable of promoting metabolic and endocrine diseases, expansion (hypertrophy or hyperplasia) leading to obesity and its complications, and deficiency as observed in lipodystrophy and cachexia. Brown adipose tissue appears to be an attractive target for the treatment of obesity.

This book intends to provide the reader with a comprehensive overview of the current knowledge about adipose tissue physiology and disorders.

Publishing process

Book initiated and editor appointed

Date completed: October 15th 2020

Applications to edit the book are assessed and a suitable editor is selected, at which point the process begins.

Chapter proposals submitted and reviewed

Deadline for chapter proposals: November 12th 2020

Potential authors submit chapter proposals ready for review by the academic editor and our publishing review team.

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Approved chapters written in full and submitted

Deadline for full chapters: January 11th 2021

Once approved by the academic editor and publishing review team, chapters are written and submitted according to pre-agreed parameters

Full chapters peer reviewed

Review results due: April 1st 2021

Full chapter manuscripts are screened for plagiarism and undergo a Main Editor Peer Review. Results are sent to authors within 30 days of submission, with suggestions for rounds of revisions.

Book compiled, published and promoted

Expected publication date: May 31st 2021

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About the editor

Hassan M. Heshmati

Endocrinology Metabolism Consulting, LLC

Hassan M. Heshmati, Medical Doctor, Endocrinologist, has 44 years of experience in clinical research in Academia (university-affiliated hospitals in Paris, France and Mayo foundation in Rochester, MN, USA) and in Pharmaceutical Companies (Sanofi, Essentialis, and Gelesis, USA). His research activity has been related to pituitary tumor, hyperthyroidism, thyroid cancer, osteoporosis, obesity, and diabetes. He has extensive knowledge in the development of anti-obesity products. He is the author of 267 presentations and publications related to Endocrinology and Metabolism. He is currently Consultant at Endocrinology Metabolism Consulting, LLC, Anthem, AZ, USA.

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Book chapters authored 2

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