Open access peer-reviewed Edited Volume

Neuroplasticity - Visual Cortex Reorganization From Neurons to Maps

Alyssa Brewer

University of California, Irvine

Dr. Brewer is a Stanford-trained physician-scientist, tenured Associate Professor at UC Irvine, and Director of the mind space Lab, who uses cutting-edge computational neuroimaging to study the organization and plasticity of the human sensory cortex.


Brian Barton

University of California, Irvine

Dr. Barton is a UCI-trained cognitive scientist who has pioneered the study of auditory field maps in the human cortex and currently focuses his research on computational neuroimaging measurements of audiovisual cortical processing and organization.


Mammalian Primate Human Genetics and Epigenetics Individual Variability Adaptation Cortical Reorganization Cortical Recovery Visual Field Map Sensorimotor Maps Bottom-Up Sensory Processing Top-Down Visual Attention

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About the book

The ultimate goal of many fields of neuroscience research is to harness the ability of the mammalian brain to reorganize. The ability to control cortical reorganization in the adult cortex, either by controlling existing adult mechanisms for plasticity or by reactivating mechanisms of developmental plasticity, would be a tremendous advancement in the treatment of cortical damage and neurodegenerative diseases. Consequently, the specifics of the timing and types of reorganization possible in the mammalian visual cortex, in particular, have consistently generated tremendous interest in both the scientific community and the general public. Few sources, however, provide a combined look into the plasticity of the visual cortex in both juvenile and adult mammalian brains.

While it is clear that visual representations in the mammalian cortex can undergo significant reorganization during an early critical period of development, the extent of reorganization possible in the developing visual cortex is still an area of active investigation. This dynamic nature of cortical circuitry is important for learning, as well as for repair following nervous system injury. Similarly, several aspects of the visual cortex are thought to remain plastic into adulthood, allowing cortical sensorimotor maps to be modified continuously by experience. Because studies of the extent of cortical reorganization in the adult mammalian visual cortex have at times produced quite disparate results, many pioneering studies are now attempting to address these controversial measurements.

This proposed book topic will examine our current understanding of the interplay of plasticity and stability in the developing and adult mammalian visual systems as well as our progress towards translating these fundamental research findings into updates for clinical practice.

Publishing process

Book initiated and editor appointed

Date completed: March 3rd 2022

Applications to edit the book are assessed and a suitable editor is selected, at which point the process begins.

Chapter proposals submitted and reviewed

Deadline Extended: Open for Submissions

Potential authors submit chapter proposals ready for review by the academic editor and our publishing review team.

Approved chapters written in full and submitted

Deadline for full chapters: July 3rd 2022

Once approved by the academic editor and publishing review team, chapters are written and submitted according to pre-agreed parameters

Full chapters peer reviewed

Review results due: September 21st 2022

Full chapter manuscripts are screened for plagiarism and undergo a Main Editor Peer Review. Results are sent to authors within 30 days of submission, with suggestions for rounds of revisions.

Book compiled, published and promoted

Expected publication date: November 20th 2022

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About the editor

Alyssa Brewer

University of California, Irvine

Dr. Alyssa A. Brewer completed her undergraduate degrees at Stanford University, with a B.S. with Honors in Biological Sciences and an A.B. in Comparative Literature with interdisciplinary Honors in Humanities. She continued on at Stanford in a dual-degree graduate program, graduating with an M.D. and a Ph.D. in Neuroscience in 2007. Her work in graduate school with Brian Wandell, Ph.D., focused on computational neuroimaging measurements of visual cortex organization and plasticity in humans and macaque. She now is an Associate Professor in the Departments of Cognitive Sciences and Language Science, by courtesy, at the University of California, Irvine. Dr. Brewer’s research focuses on visual, auditory, and multi-sensory neuroscience, using behavioral, genetic, and high-resolution neuroimaging techniques to investigate questions ranging from the fundamental organization of human visual and auditory cortex to plasticity in visual, auditory, and sensorimotor regions.

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Book chapters authored 6

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