Open access peer-reviewed Edited Volume

Homology Molecular Modeling - Perspectives and Applications

Rafael Maia

Federal University of Campina Grande


Rômulo Moraes Filho

Federal Rural University of Pernambuco

Magnólia Campos

Federal University of Campina Grande


3D Modeling Servers 3D Modeling Programs Databases Algorithms Structural Assessment Energy Minimization Structural Stability Force-fields Molecular Dynamics Molecular Docking Protein Engineering Binding-site Prediction

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About the book

Molecular modeling is a multidisciplinary field of knowledge that has revolutionized several areas. One of the most used techniques in this subject is called " Homology Modeling " or "Comparative Modeling", whose aim is to elucidate comparatively three-dimensional structures of proteins using their primary amino acid sequence. Knowing the structure of a protein is essential to know details of its functionality, and due to this importance, more and more theoretical models are built for several purposes, such as molecular docking simulations, molecular dynamics studies, protein engineering, peptide design , etc.

There are currently numerous tools and databases that can be used for the construction and validation of three-dimensional models. In this book, meticulously selected works are available that applied in their research the homology modeling technique for structure elucidation. The rapid advancement of scientific computing, associated with the growing number of experimentally elucidated structures available in databases such as the PDB-Protein Data Bank, has made the use of this technique increasingly common in scientific works.

Protein modeling has a promising and challenging future ahead, with promises to promote development in several sectors. The current work was edited thinking about this intriguing future of molecular modeling.

Publishing process

Book initiated and editor appointed

Date completed: June 17th 2020

Applications to edit the book are assessed and a suitable editor is selected, at which point the process begins.

Chapter proposals submitted and reviewed

Deadline Extended: Open for Submissions

Potential authors submit chapter proposals ready for review by the academic editor and our publishing review team.

Approved chapters written in full and submitted

Deadline for full chapters: September 6th 2020

Once approved by the academic editor and publishing review team, chapters are written and submitted according to pre-agreed parameters

Full chapters peer reviewed

Review results due: November 25th 2020

Full chapter manuscripts are screened for plagiarism and undergo a Main Editor Peer Review. Results are sent to authors within 30 days of submission, with suggestions for rounds of revisions.

Book compiled, published and promoted

Expected publication date: January 24th 2021

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About the editor

Rafael Maia

Federal University of Campina Grande

Dr. Rafael Maia studied biological sciences at the Federal Rural University of Pernambuco, Brazil (2005), got a Master´s degree in genetics, conservation, and evolutionary biology from the National Institute of Amazonian Research, Brazil (2008), and a Ph.D. in animal biology from the Federal University of Pernambuco, Brazil (2013). He is currently an adjunct professor at Center for the Sustainable Development of the Semi-Arid (CDSA) at Federal University of Campina Grande (UFCG), Brazil. He has experience with population genetics, bioinformatics, molecular docking, and modeling and molecular dynamics of proteins. He works in the area of ​​science and biology education. He leads the research groups Computational and Theoretical Biology (CTB) and Education in Sciences and Biology (ESB).

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Book chapters authored 2

Books edited 1

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