About the book
Molecular modeling is a multidisciplinary field of knowledge that has revolutionized several areas. One of the most used techniques in this subject is called " Homology Modeling " or "Comparative Modeling", whose aim is to elucidate comparatively three-dimensional structures of proteins using their primary amino acid sequence. Knowing the structure of a protein is essential to know details of its functionality, and due to this importance, more and more theoretical models are built for several purposes, such as molecular docking simulations, molecular dynamics studies, protein engineering, peptide design , etc.
There are currently numerous tools and databases that can be used for the construction and validation of three-dimensional models. In this book, meticulously selected works are available that applied in their research the homology modeling technique for structure elucidation. The rapid advancement of scientific computing, associated with the growing number of experimentally elucidated structures available in databases such as the PDB-Protein Data Bank, has made the use of this technique increasingly common in scientific works.
Protein modeling has a promising and challenging future ahead, with promises to promote development in several sectors. The current work was edited thinking about this intriguing future of molecular modeling.