Open access peer-reviewed Edited Volume

Neurorehabilitation (and Neural Repair) - Advanced Diagnosis and Recovery Options

Denis Larrivee

Loyola University Chicago


Cortical Activity Overlap Multiple Sclerosis Ischemic stroke Brain trauma Externalized Mechanical Assistance Devices Machine learning Large scale data analysis Stimulation Approaches Interhemispheric functional connectivity Sensory Evoked Potentials Language-dependent Motor Fluency Motor Cortex MEG

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About the book

Neurorehabilitation is among the most significant and actively investigated domains of central nervous system impairments today. Underlying factors are multiple, but begin with the knowledge that brain dysfunction is widely variable and highly prevalent in the general population. Vascular disorders, such as ischemic strokes or subdural hematomas, degenerative diseases like Parkinsons, ALS, or multiple sclerosis, infections like meningitis, trauma, and structural and functional disorders all contribute to brain pathologies. Combined with extraordinary strides in structural and physiological brain diagnosis, which merge neuroimaging with functionally linked mathematical models, this need for intervention has stimulated the development of a spectrum of strategic approaches to neurorehabilitation. Often involving an array of neurotechnological interventions these span the range from external motor enhancing exoskeletons to brain communication and modulation technology. Indeed there is growing consensus that functional recovery is in many cases achievable, either through assisted replacements, or neural restoration. Among the most promising developments for replacing function is the greatly improved ability to interpret relevant brain activity through machine learning techniques like deep learning and to analyze large scale data regimes. Coupled with robotic devices through computer interfacing, these are enabling patients to overcome cognitive and, especially, impaired motor abilities. Frequently pursued strategies for restoration, moreover, avail the intrinsic plasticity of brain activity. Through neurofeedback, for example, restoration strategies incorporate the patient as an integral component of the repair loop, where he can both monitor and accelerate his recovery. In other cases non-invasive neurostimulatory protocols, such as tDCS are inducing plastic mechanisms that activate or establish new functional channels.

This book intends to offer a comprehensive review of current neurorehabilitation approaches and advanced strategies for the professional researcher and therapist. 

Publishing process

Book initiated and editor appointed

Date completed: November 12th 2019

Applications to edit the book are assessed and a suitable editor is selected, at which point the process begins.

Chapter proposals submitted and reviewed

Deadline Extended: Open for Submissions

Potential authors submit chapter proposals ready for review by the academic editor and our publishing review team.

Approved chapters written in full and submitted

Deadline for full chapters: February 1st 2020

Once approved by the academic editor and publishing review team, chapters are written and submitted according to pre-agreed parameters

Full chapters peer reviewed

Review results due: April 21st 2020

Full chapter manuscripts are screened for plagiarism and undergo a Main Editor Peer Review. Results are sent to authors within 30 days of submission, with suggestions for rounds of revisions.

Book compiled, published and promoted

Expected publication date: June 20th 2020

All chapters are copy-checked and typesetted before being published. IntechOpen regularly submits its books to major databases for evaluation and coverage, including the Clarivate Analytics Book Citation Index in the Web of ScienceTM Core Collection. Other discipline-specific databases are also targeted, such as Web of Science's BIOSIS Previews.

About the editor

Denis Larrivee

Loyola University Chicago

Dr. Denis Larrivee is a Visiting Scholar at the Mind and Brain Institute, University of Navarra Medical School and Loyola University Chicago and has held professorships at the Weill Cornell University Medical College, NYC, and Purdue University, Indiana. A former fellow at Yale University's Medical School he received the Association for Research in Vision and Ophthalmology's first place award for studies on photoreceptor degenerative and developmental mechanisms. He is the editor of a recently released text on Brain Computer Interfacing with InTech Publishing and an editorial board member of the journals Annals of Neurology and Neurological Sciences (USA) and EC Neurology (UK). An International Neuroethics Society Expert he is the author of more than 80 papers and book chapters in such varied journals/venues as Neurology and Neurological Sciences (USA), Journal of Neuroscience, Journal of Religion and Mental Health, and IEEE Explore. In 2018 he was a finalist in the international Joseph Ratzinger Expanded Reason award.

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