Open access peer-reviewed Edited Volume

Filariasis

Tonay Inceboz

Dokuz Eylül University

Covering

ilariasis morphology vector geographic distribution Lymphatic system Wuchereria bancrofti Brugia malayi Brugia timori Cutaneous and ocular system Dipetolonema streptocerca Loa loa Onchocerca volvulus Serous cavity Mansonella perstans and Mansonella ozzardi Dirofilaria immitis Other filariae Dipetolonema perstans Dipetolonema streptocerca Dracunculus medinensis microscopy serology molecular drugs prevention

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About the book

Filariasis is an unregarded tropical disease in the world; and it is the most prevalent cause for secondary lymphedema. The parasites causing Filariasis are microscopically long filarial nematods. Depending on the type of the filarial worm, the infection may occur in the lymphatic system, subcutaneous tissues, deep connective tissues or conjunctiva. Filarial nematods are different from other nematods by being viviparous. Definite hosts of filariae are humans. Transmission to humans may be via different vectors; female mosquitoes being the the main one.
Main types of important health problems that occur in humans are: Wuchereria bancrofti, Brugia malayi, Brugia timori, Onchocerca volvulus, Loa loa, Mansonella ozzardi, Dipetolonema perstans, Dipetolonema streptocerca, Dirofilaria repens, Dirofilaria tenuis, Dirofilaria immitis, and Dracunculu smedinensis.
Epidemiologically Filarisis is estimated to be prevalent in more than 120 million people worldwide. Mostly it is prevalent in hot and humid subtropical regions. Countries where filariasis may be found in Asia: Amman, China, India, Japan, Korea, Vietnam, Indonesia, Ceylon, Malaysia and Thailand; in the Mediterranean region: Spain, Italy, Macedonia; in Africa: (between 150 North and 130 South parallels) Angola, Tanzania, Ghana, Morocco, Algeria, Tunis, Egypt; and in Central America: Mexico, Honduras, Venezuela, Caribbean, Guyana.
Clinical manifestation may vary from painful inflammatory swellings of lymph nodes in acute infections to lymphedema due to blockage of lymphatic system in chronic cases. The diagnosis firstly depends on the “suggestive symptoms”. Blood tests such as Indirect Hemaglutination (IHA), Enzym-Linked Immunosorbent Assay (ELISA) are indirect diagnostic tests and PCR. Definitive diagnosis depends on direct identification of microfilariae in blood samples or involved-tissue biopsies. The treatment of choice in Filariasis is a combined regimen of diethylcarbamazine (DEC) 6 mg/kg, ivermectin 150 mg/kg and albendazole (ALB) 400 mg single-administration. Prevention: Treatment of patients with filariasis and vector control is possible 

Publishing process

Book initiated and editor appointed

Date completed: September 10th 2019

Applications to edit the book are assessed and a suitable editor is selected, at which point the process begins.

Chapter proposals submitted and reviewed

Deadline Extended: Open for Submissions

Potential authors submit chapter proposals ready for review by the academic editor and our publishing review team.

Approved chapters written in full and submitted

Deadline for full chapters: November 30th 2019

Once approved by the academic editor and publishing review team, chapters are written and submitted according to pre-agreed parameters

Full chapters peer reviewed

Review results due: February 18th 2020

Full chapter manuscripts are screened for plagiarism and undergo a Main Editor Peer Review. Results are sent to authors within 30 days of submission, with suggestions for rounds of revisions.

Book compiled, published and promoted

Expected publication date: April 18th 2020

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About the editor

Tonay Inceboz

Dokuz Eylül University

Tonay Inceboz, a senior lecturer in Medical Parasitology, has graduated from Ege University of Medical Faculty (Turkey) in 1988 and completed his Med. PhD degree in Medical Parasitology at the same university in 1998. He became an Associate Professor in 2008 and a Professor in 2014. He is currently working as a Professor at the Department of Medical Parasitology at Dokuz Eylul University, Izmir, Turkey. His main research interests are Echinococcus granulosus, Echinococcus multilocularis (diagnosis, life cycle, in vitro and in vivo cultivation), and Trichomonas vaginalis (diagnosis, PCR, and in vitro cultivation).

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