About the book
With the beginning of 21st century, interest of researchers started growing in understanding the complex phenomena of how cells renew themselves and communicate with one another. This made research into the field of cell division and cell signalling see significant progress. It is because of the fundamental cellular requirement of division and communication by the cells the research in cell signaling pathways and cell division associated proteins has always occupied a cornerstone position. Among these proteins, the protein P53 has remained the “best friend” of cellular biologists because of its amazing ability to regulate cell division and control apoptosis. P53 is the most extensively researched protein in cell biology and has been investigated in relation to cell cycle control, apoptosis, neurodegeneration, immune system and many other processes. The most well-known role of P53 remains as a tumor suppressor (gate keeper) and its de-regulation has been shown to be involved in various forms of cancer. However, with the introduction of recent technological advancements in research, role of P53 is slowly being re-written as a protein which is multi-faceted in its action.
This book talks at length about the classical roles of P53 since its discovery and navigates through its most recent and non-canonical functions, as supported by recent evidences and research across diverse fields of interest.