About the book
The central nervous system (CNS) is composed of many cell types and nearly each can divide abnormally and develop into a tumor. These tumors can be benign or malignant and are treated differently depending on their type and location. Of the primary CNS tumors, gliomas are the most infiltrative and therefore the most difficult to treat. Low-grade gliomas can transform into higher-grade tumors with a poorer prognosis. Standard of care for malignant gliomas typically consists of a multimodal approach including surgery, chemo- and radiation therapy, and tumor treating fields. Genetic targets as well as immunotherapy and tumor vaccines offer other avenues to pursue. Meningiomas are typically benign lesions that can nonetheless cause symptoms depending on their location. Higher grade meningiomas typically have a poorer prognosis. Vestibular schwannomas are also benign tumors that can affect both hearing and balance. Tumors intrinsic to the spine, as well as intra- or extradural tumors cause significant morbidity, as well.
The purpose of this book will be to discuss the most commonly encountered CNS tumors with a discussion of their genetics, symptoms, and treatments.