Open access peer-reviewed Edited Volume

RNA Viruses

Yogendra Shah

National Zonosis and Food Hygience Research Center

Covering

Structure of RNA Viruses Host Response to RNA Viral Infection RNA Virus Evolution Reverse Genetics of RNA Viruses Reverse Transcriptase Viral Disease Vaccine Anti-viral Drugs Diagnostics Tools for Detection RNA Viruses Vector Borne Diseases Control Prevention

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About the book

RNA viruses are classified according to their sense or polarity of RNA into Plus-Strand RNA viruses, Minus-Strand RNA viruses and also genome can be classified as single stranded, double stranded or fragmented. Most of RNA viruses replicate and are assembled in the cytoplasm but DNA viruses replicate and are assembled in the nucleus of the host cell. Medically important RNA viruses are; Togavirus, Bunyavirus, Flavivirus, Filovirus, Arenavirus,Rhabdovirus,Paramyxovirus, Orthomyxovirus, Coronavirus, Retrovirus, Picornavirus, Reovirus and Calicivirus. Several human diseases are caused by RNA viruses. Among RNA viruses, Flaviviridae family is considered as one of potential and emerging international public health problem in worldwide. Flavivirus genus of the Flaviviridae family comprises dengue virus, yellow fever virus, chikungunya virus, Japanese encephalitis virus, Zika virus etc. Flavivirus may manifest mild symptoms such as malaise, fever and joint pain, with a maculopapular rash commonly found on the body. However, pathogenesis mechanism causing viral diseases among the Falvivirus family has not been clearly understood and also little know about the host responses to RNA viral infection.

The main aim of this book will to understand the RNA viruses (such as Flaviviridae family), through seroprevalence status, research studies based on molecular genotyping tools by IgM/IgG, ELISA, PCR, FRNT50 and phylogenetic analysis.

Publishing process

Book initiated and editor appointed

Date completed: October 29th 2019

Applications to edit the book are assessed and a suitable editor is selected, at which point the process begins.

Chapter proposals submitted and reviewed

Deadline Extended: Open for Submissions

Potential authors submit chapter proposals ready for review by the academic editor and our publishing review team.

Approved chapters written in full and submitted

Deadline for full chapters: May 15th 2020

Once approved by the academic editor and publishing review team, chapters are written and submitted according to pre-agreed parameters

Full chapters peer reviewed

Review results due: August 3rd 2020

Full chapter manuscripts are screened for plagiarism and undergo a Main Editor Peer Review. Results are sent to authors within 30 days of submission, with suggestions for rounds of revisions.

Book compiled, published and promoted

Expected publication date: October 2nd 2020

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About the editor

Yogendra Shah

National Zonosis and Food Hygience Research Center

Dr. Yogendra Shah, born in Kanchanpur, Nepal, received his Doctor of Philosophy (PhD) degree in 2017 from Hokkaido University, Japan. At present, he is working in the capacity of Senior Research Microbiologist and Lecturer position at National Zoonoses and Food Hygiene Research Center and Kathmandu College of Science and Technology, Nepal. He has worked more than seven years at different research centers as a research microbiologist (Everest international clinic and research Center /National Zoonoses and Food Hygiene Research Center) in the field of infectious diseases in Nepal. He has been involved in several research works on Dengue virus, Hepatitis C virus, Herpes simplex virus-2, Japanese encephalitis virus, HIV, Tuberculosis, Toxoplasmosis, Brucellosis, Toxoplasmosis, Leptospirosis, Echinococcosis, Cysticercosis, Leishmania (Kalazar), Chylamida and Nesseria. He completed his Doctor of Philosophy (PhD) in Veterinary Medicine (Bacteriology) at Division of Bioresources, Research center for Zoonosis control, Hokkaido University, Japan. The main focus during his PhD research study was to better understand the molecular epidemiological features and transmission dynamics of multi-drug resistant Mycobacterium tuberculosis (MTB) Beijing/CAS families isolates from Nepal i.e. spoligotyping, mycobacterial interspersed repetitive unit-variable number tandem repeat (MIRU-VNTR), DNA sequencing and whole genome sequencing (Miseq). He had also worked as visiting researcher position after he completed his PhD on leprosy control project, at Division of Bioresources, Research center for Zoonosis control, Hokkaido University, Japan from October 2017 to March 2018. The main purpose of research leprosy control project was to build the capacity in drug resistant leprosy research and also to work on collaborative research for zoonosis control in Nepal. He had been offered with leading role in planning laboratory work and diagnosis based on serological and molecular techniques. He received Japanese government scholarship award (2013) to (2017) for PhD study. His research interests include infectious diseases, zoonotic infectious diseases and vector borne diseases. He has published 34 research articles and 3 books.

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