Open access peer-reviewed Edited Volume

Tumor Microenvironment - New Insights

Ahmed Lasfar

Rutgers, The State University of New Jersey

Dr. Lasfar is a member of the Cancer Institute of New Jersey, a Principal Investigator, and a faculty member at Rutgers University, USA. He graduated in France from Paris Rene Descartes University and he has completed his doctoral studies in Immunology at Paris Diderot University, France. He received several awards including two excellence scientific awards from the New Jersey Commission on Cancer Research and one award from the International Society for Interferon and Cytokine Research.


Cancer Cells Surrounding Cells Cancer Progression Metastasis Cancer Immunity Immune Cells Innate Immunity Adaptive Immunity Mechanisms of Cell Signaling Tumor Immune Toxicity Factors Expression Modulation of Signaling

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About the book

The tumor microenvironment (TME) is critical for cancer cells' growth and progression. TME includes several non-malignant cell types that surround and interact with cancer cells. Those surrounding cells include immune and non-immune cells, physically interact with cancer cells and shape the TME by initiating important signals and inducing many important factors. The significance of cell interactions between non-malignant and cancer cells in TME is crucial in understanding the mechanisms of carcinogenesis and metastasis. The role of immune cells in TME and the mechanisms, related to cancer resistance is currently under intense investigation. Several cancer insights are demonstrated, including the mechanisms of immune escapes. Our advanced understanding of TME is the basis of many successful cancer treatments and the future of targeted immunotherapies.

Publishing process

Book initiated and editor appointed

Date completed: April 21st 2022

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Chapter proposals submitted and reviewed

Deadline Extended: Open for Submissions

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Approved chapters written in full and submitted

Deadline for full chapters: July 18th 2022

Once approved by the academic editor and publishing review team, chapters are written and submitted according to pre-agreed parameters

Full chapters peer reviewed

Review results due: October 6th 2022

Full chapter manuscripts are screened for plagiarism and undergo a Main Editor Peer Review. Results are sent to authors within 30 days of submission, with suggestions for rounds of revisions.

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Expected publication date: December 5th 2022

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About the editor

Ahmed Lasfar

Rutgers, The State University of New Jersey

Dr. Ahmed Lasfar is a Cancer Immunologist and a leading expert on melanoma. He is a full member of the Rutgers-Cancer Institute of New Jersey, principal investigator, and a faculty member at Ernest Mario School of Pharmacy, Rutgers University, New Jersey. Dr. Lasfar’s laboratory focuses on understanding the immune mechanisms controlling cancer development and metastasis. In addition to melanoma, Dr. Lasfar’s laboratory is studying hepatocellular carcinoma and breast cancer. Dr. Lasfar has edited several books and research topics in cancer. He is an editor, board member, and reviewer of relevant international journals and foundations. Dr. Lasfar also serves as a consultant scientific adviser for the pharmaceutical industry. Dr. Lasfar obtained his undergraduate and graduate degrees in France from Paris Rene Descartes University and Denis Diderot University. He completed his postdoctoral training in cancer immunology at Robert Wood Johnson Medical School in New Jersey.

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Book chapters authored 4

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