About the book
The importance of leptin – a hormone made by adipocytes and enterocytes – in regulating energy balance cannot be undervalued. Leptin deficiency is related to obesity, metabolic disorders, type II diabetes, and cardiovascular disease. It is also linked with an altered gut microbiome and increased susceptibility to intestinal pathogens. The signaling role in intestinal epithelium in defense against intestinal pathogens suggests that leptin could be possibly used as an adjuvant tool in vaccines to promote gut immunity.
This book intends to provide newer advancements in the research of leptin’s role in intestinal dysbiosis and possible use as a vaccine candidate to protect from intestinal dysbiosis which is the cause of various diseases and conditions. The book is an attempt to understand leptin through evidence-based developments in this critically important area of human health, and it is imagined as a valuable guide for researchers and clinicians interested in intestinal immunity.