Open access peer-reviewed Edited Volume

NRF2 and Oxidative Stress

Jose Antonio Morales-Gonzalez

Instituto Politécnico Nacional


Eduardo Osiris Madrigal-Santillan

Instituto Politécnico Nacional

Ángel Morales-González

Instituto Politécnico Nacional

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Liliana Anguiano Robledo

Instituto Politécnico Nacional


Antioxidant Response Elements Oxidative Stress Partial Hepatectomy Ethanol Metabolism Neurodegenerative Diseases Cancer Endogenous Antioxidants Cytoprotection Chemoprevention Genoprotection CAT Antioxidant Enzymes

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About the book

Aerobic organisms like human beings have several metabolic pathways connected to the process of obtaining energy that use oxygen as the final electron acceptor. Therefore, this is essential for the existence of the condition of life. Paradoxically, under certain conditions in which the reduction intermediaries, mainly oxygen, accumulate, so-called free radicals are produced, capable of producing damage at the molecular level, which manifests itself in various chronic pathologies.
The transcriptional factor Nrf2 is a regulator of cytoprotection - for example, of antioxidant enzymes, pro-inflammatory cytokines, apoptosis, detoxification, proliferative processes, etc. At present, it is unknown how Nrf2 is regulated, both in physiological and pathological conditions.Therefore, it is essential to understand the mechanism by which Nrf2 is regulated. This book aims to give the scientific community the opportunity to disseminate their research and readers to deepen or expand their understanding in this field of knowledge. Potential authors are encouraged to expand the list of topics as best suits them in order to present the new scientific advances on Nrf2 and its regulation in oxidative stress.

Publishing process

Book initiated and editor appointed

Date completed: February 20th 2019

Applications to edit the book are assessed and a suitable editor is selected, at which point the process begins.

Chapter proposals submitted and reviewed

Deadline Extended: Open for Submissions

Potential authors submit chapter proposals ready for review by the academic editor and our publishing review team.

Approved chapters written in full and submitted

Deadline for full chapters: May 12th 2019

Once approved by the academic editor and publishing review team, chapters are written and submitted according to pre-agreed parameters

Full chapters peer reviewed

Review results due: July 31st 2019

Full chapter manuscripts are screened for plagiarism and undergo a Main Editor Peer Review. Results are sent to authors within 30 days of submission, with suggestions for rounds of revisions.

Book compiled, published and promoted

Expected publication date: September 29th 2019

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About the editor

Jose Antonio Morales-Gonzalez

Instituto Politécnico Nacional

José Antonio Morales-González graduated as a Surgeon Physician from FES-Iztacala, National Autonomous University of Mexico (UNAM). He engaged in Doctoral studies in Biological Sciences at the UNAM. Dr Morales-González has been awarded diverse recognitions: the Gustavo Baz Prada Medal by the UNAM, the Alfonso Caso Medal for academic merit by the UNAM, and was recognized by the National System of Researchers (SNI) as National Researcher Level 2 (2017-2020). In addition to this, he has served as director for 16 undergraduate and 46 postgraduate theses. He is the author of 50 internationally published articles, with more than 900 citations to these publications. He is also the editor and coordinator of 28 specialized books and is the author of 41 chapters in specialized books. Dr Morales-González is a Full-time Tenured Professor-Researcher at the Escuela Superior de Medicina, IPN.

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Book chapters authored 7

Books edited 5

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