Open access peer-reviewed Edited Volume

Gene Expression and Phenotypic Traits


Shiu-Jau Chen

Mackay Medical College


RNA Polymerase Promoter Genetic Code Ribosome Translational Regulation Protein Processing Inducible Gene Constitutive Gene RNA Quantification Protein Quantification Epigenetic Multiple Alleles

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About the book

Gene expression is a process by which the genetic information is used in the synthesis of functional products including proteins and functional RNAs (e.g., tRNA, small nuclear RNA). This process is utilized by eukaryotes, prokaryotes and viruses to generate macromolecules for constituting cellular components and exhibiting living functions. Several steps in gene expression process could be regulated, such as transcription, post-transcriptional modification, translation, and post-translational modification. Regulation of gene expression modulates the production amount and timing of the functional products. Control of gene expression is critical to allow cells to produce their functional products when cells need them; in turn, this gives cells the flexibility to adapt to a variable environment and respond to external signals, stimuli and damages. Cellular structures and functions can also be controlled by regulation of gene expression. A phenotypic trait, the expression of genes in an observable way, is an obvious and measurable trait. The phenotype is variable which depends on the genetic make-up of the organism, and also that is influenced by the surroundings to which the organism is subjected across its morphogenesis, (including various epigenetic processes). In this book, we will explore the significance, mechanism, function and characteristics of gene expression and phenotypic traits. 

Publishing process

Book initiated and editor appointed

Date completed: August 6th 2019

Applications to edit the book are assessed and a suitable editor is selected, at which point the process begins.

Chapter proposals submitted and reviewed

Deadline Extended: Open for Submissions

Potential authors submit chapter proposals ready for review by the academic editor and our publishing review team.

Approved chapters written in full and submitted

Deadline for full chapters: October 26th 2019

Once approved by the academic editor and publishing review team, chapters are written and submitted according to pre-agreed parameters

Full chapters peer reviewed

Review results due: January 14th 2020

Full chapter manuscripts are screened for plagiarism and undergo a Main Editor Peer Review. Results are sent to authors within 30 days of submission, with suggestions for rounds of revisions.

Book compiled, published and promoted

Expected publication date: March 14th 2020

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About the editor

Yuan-Chuan Chen

Yuan-Chuan Chen completed his PhD in Comparative Biochemistry at the University of California, Berkeley (UCB), USA and had postdoctoral studies at the Taiwan Food and Drug Administration (TFDA). His research interests include Pharmacy/Pharmacology, Biochemistry, Microbiology/Virology, Cell/Molecule Biology, Biotechnology/Nanotechnology, Cell/Gene therapy and Policy/Regulation. He has participated in publishing many co-authored articles in peer-reviewed journals and book chapters in the fields of basic science, biomedicine, and related policy/regulation. He is now an assistant researcher at National Applied Research Laboratories (NARL), Taiwan. He is also an adjunct member in the biopharmaceutical division of Chinese Pharmacopoeia (Taiwan) Revising Committee (9th edition) and has reviewed many materials for Pharmacopoeia revising. His research is focusing on the discovery, production, application, perspectives and challenges of biopharmaceuticals. He is interested in basic research, the development of agricultural/industrial products and human therapeutics using the CRISPR/Cas9 system. Additionally, he is specialized in genomic studies including genomic analysis, gene function, and gene expression and control.

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Book chapters authored 5

Books edited 1

Introducing your Author Service Manager

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As an Author Service Manager my responsibilities include monitoring and facilitating all publishing activities for authors and editors. From chapter submission and review, to approval and revision, copyediting and design, until final publication, I work closely with authors and editors to ensure a simple and easy publishing process. I maintain constant and effective communication with authors, editors and reviewers, which allows for a level of personal support that enables contributors to fully commit and concentrate on the chapters they are writing, editing, or reviewing. I assist authors in the preparation of their full chapter submissions and track important deadlines and ensure they are met. I help to coordinate internal processes such as linguistic review, and monitor the technical aspects of the process. As an ASM I am also involved in the acquisition of editors. Whether that be identifying an exceptional author and proposing an editorship collaboration, or contacting researchers who would like the opportunity to work with IntechOpen, I establish and help manage author and editor acquisition and contact.

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