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Open access peer-reviewed Edited Volume

Structural and Molecular Aspects of DNA Repair

Subrata Dey

West Bengal University of Technology

A pioneering researcher on Down syndrome and genetic aspects of congenital heart defects, Alzheimer’s disease, and radiation-induced genomic instability. Appointed Vice-Chancellor of Swami Vivekananda University, holder of one registered patent and author of more than a hundred papers.

Covering

DNA Repair Pathways DNA Repair Enzymes Premature Ageing Cancer Inherited Human Disorders Mutation Cell Cycle Telomere Maintenance Telomere Damage Physical Agents Chemical Agents Alkylating Agents
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Structural and Molecular Aspects of DNA Repair

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About the book

DNA is continuously exposed to a myriad of physical and chemical agents that damage the DNA and impact the health and condition of living organisms. However, DNA repair enzymes faithfully protect the DNA and preserve the genomic sequence information. In many cancers, DNA repair pathways are disrupted and deregulated, and that results in genomic instability. Besides cancer, other human diseases are also caused due to unresolved DNA damage. However, robust DNA repair and damage tolerance pathways help remove or tolerate the lesions to allow survival.

This book aims to highlight the mechanisms of DNA repair, enzymes involved in repairing the damaged DNA, consequences of toxic exposures, diseases, and recent advances in research regarding the DNA repair mechanisms. This book will also provide the reader with a comprehensive overview of the DNA repair mechanisms, enzymes involved, and pathological consequences of the damage caused by physical and chemical agents on DNA.

Publishing process

Book initiated and editor appointed

Date completed: February 15th 2022

Applications to edit the book are assessed and a suitable editor is selected, at which point the process begins.

Chapter proposals submitted and reviewed

Deadline Extended: Open for Submissions

Potential authors submit chapter proposals ready for review by the academic editor and our publishing review team.

Approved chapters written in full and submitted

Deadline for full chapters: June 19th 2022

Once approved by the academic editor and publishing review team, chapters are written and submitted according to pre-agreed parameters

Full chapters peer reviewed

Review results due: September 7th 2022

Full chapter manuscripts are screened for plagiarism and undergo a Main Editor Peer Review. Results are sent to authors within 30 days of submission, with suggestions for rounds of revisions.

Book compiled, published and promoted

Expected publication date: November 6th 2022

All chapters are copy-checked and typesetted before being published. IntechOpen regularly submits its books to major databases for evaluation and coverage, including the Clarivate Analytics Book Citation Index in the Web of ScienceTM Core Collection. Other discipline-specific databases are also targeted, such as Web of Science's BIOSIS Previews.

About the editor

Subrata Dey

West Bengal University of Technology

Prof. Subrata Kumar Dey, Ph.D, Vice Chancellor, Swami Vivekananda University, West Bengal, India has been associated with teaching and research for more than four decades and had visited different countries as invited speaker for delivering lectures. He joined as Professor of Biotechnology in Maulana Abul Kalam Azad University of Technology and was ex- Director of School of Biotechnology and Biological Sciences . His laboratory had long been involved in research on molecular genetics of Down syndrome, congenital heart disease and Alzheimer’s disease. He published more than hundred research papers, edited several books on Down syndrome and had completed eleven research projects. Several students obtained Ph.D under his supervision. Along with teaching and research , Prof. Dey handled a number of administrative assignments successfully and had made dedicated and innovative approaches with great integrity. His major administrative roles were Director of Centre for Genetic Studies, Pro-Vice Chancellor and Vice Chancellor, Maulana Abul Kalam Azad University of Technology, India.

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Book chapters authored 6

Books edited 6

Introducing your Author Service Manager

M.Sc. Iva Ribic

As an Author Service Manager my responsibilities include monitoring and facilitating all publishing activities for authors and editors. From chapter submission and review, to approval and revision, copyediting and design, until final publication, I work closely with authors and editors to ensure a simple and easy publishing process. I maintain constant and effective communication with authors, editors and reviewers, which allows for a level of personal support that enables contributors to fully commit and concentrate on the chapters they are writing, editing, or reviewing. I assist authors in the preparation of their full chapter submissions and track important deadlines and ensure they are met. I help to coordinate internal processes such as linguistic review, and monitor the technical aspects of the process. As an ASM I am also involved in the acquisition of editors. Whether that be identifying an exceptional author and proposing an editorship collaboration, or contacting researchers who would like the opportunity to work with IntechOpen, I establish and help manage author and editor acquisition and contact.

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