Open access peer-reviewed Edited Volume

Antimicrobial Immune Response

Maria Del Mar Ortega-Villaizan

Miguel Hernandez University

Dr. Ortega-Villaizan's current research interests are the red blood cells of fish, and their involvement in fish immune response, as target cells in the search of therapies or prophylactics against fish viral infections.


Veronica Chico

Miguel Hernandez University

Dr. Chico acquired her Ph.D. in Molecular and Cell Biology at the Institute of Research, Development, and Innovation in Healthcare Biotechnology in Elche. She is working in a project funded by an ERC Starting Grant, granted to Dr. Maria del Mar Ortega-Villaizan.


Antiviral Immune Response Innate Immunity Adaptive Immunity Immune Cells Antibacterial Immune Response Antimicrobial Therapeutics Prophylactics Microbial Infections Pattern-Recognition Receptors Humoral Mechanisms Cellular Mechanisms Immune-Reactive Organs

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About the book

The innate immune system detects microbial infections by means of pattern-recognition receptors and triggers the activation of innate and adaptive immune responses in order to remove the pathogen from the organism. Protection against infectious diseases may be mainly conveyed by humoral or cellular mechanisms or by a combination of both.

The aim of this book is to collect the up to date investigations regarding the humoral and/or cellular mechanisms responsible for the induction of the antiviral and antibacterial immune responses, in the different immune-reactive organs. For example skin, lungs, gut, bone marrow, kidney, spleen, blood, liver, and reproductive organs.

Additionally, this book aims to provide the reader with an overview of the mechanisms that have been the target of interest, in terms of therapeutics or prophylactics against viral or bacterial infections. The purpose of this book is to show an up to date revision of the antimicrobial mechanisms triggered across different animal species, from invertebrates to mammals.

Publishing process

Book initiated and editor appointed

Date completed: September 11th 2020

Applications to edit the book are assessed and a suitable editor is selected, at which point the process begins.

Chapter proposals submitted and reviewed

Deadline for chapter proposals: October 9th 2020

Potential authors submit chapter proposals ready for review by the academic editor and our publishing review team.

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Approved chapters written in full and submitted

Deadline for full chapters: December 8th 2020

Once approved by the academic editor and publishing review team, chapters are written and submitted according to pre-agreed parameters

Full chapters peer reviewed

Review results due: February 26th 2021

Full chapter manuscripts are screened for plagiarism and undergo a Main Editor Peer Review. Results are sent to authors within 30 days of submission, with suggestions for rounds of revisions.

Book compiled, published and promoted

Expected publication date: April 27th 2021

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About the editor

Maria Del Mar Ortega-Villaizan

Miguel Hernandez University

Dr. Ortega-Villaizan obtained her degree in Biological Sciences (1995) from the University of Alicante (Spain) and her Ph.D. in Agricultural Sciences (about Fish Population Genetics) at the University of Tohoku, Japan (2005). In her postdoctoral period, she started working as a researcher at the University Miguel Hernandez (UMH), Elche (Spain), at the Institute of Research, Development, and Innovation in Healthcare Biotechnology in Elche (IDiBE). Dr. Ortega-Villaizan was working as a postdoctoral researcher in what would be her current research line, which is the search of therapies and prophylactics against viral pathologies in aquaculture, specifically in the context of the fish immune response. In 2014, she was granted with an ERC Starting Grant, which started in 2015 at the IDiBE (UMH). Dr. Ortega-Villaizan was leading her own laboratory, to investigate the crosstalk between red and white blood cells in the context of viral infections and DNA vaccine immunizations, in order to elucidate the role of red blood cells in the fish immune response. In 2018, she became an Assistant Professor in the Department of Biochemistry and Molecular Biology at the UMH. Her current research interests are the red blood cells of fish, and their involvement in fish immune response, as target cells in the search of therapies or prophylactics against fish viral infections.

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