Open access peer-reviewed Edited Volume

In-Situ Hybridization - From Current to Further Applications

Marcelo Larramendy

National University of La Plata


Sonia Soloneski

National University of La Plata


Methodological Approaches Basic Applications Fluorescence ISH Non-Fuorescence ISH Chromosomal Integrity Chromosomal Damage Chromosomal Rearrangements Microarrays ISH Diagnostic/Prognostic Value Tumorigenesis Chromosomal Evolution Species Speciation

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About the book

The book "In-Situ Hybridization - From Current to Further Applications" is intended to provide an overview of emerging researchable issues related to the involvement of classical and novel in-situ hybridization methodologies that highlight recent research activities not only in the molecular cytogenetics of human neoplasias but also in species speciation.
The book will cover some general and specific aspects related with the generation, use and further perspectives derived in the field. Accordingly, the following different topics will be included such as, a) Core techniques; b) History landmarks; c) Applications for conventional and non-conventional organisms; d) Applications for genetic anomalies and medical science; e) ISH and cancer research and, finally, f) ISH and species evolution.
We shall aim to compile information from a diversity of sources to give some real examples extending the concepts in in-situ hybridization as a crucial step for understanding the organization, regulation and function of genes, thus stimulating new research ideas and trends in the relevant fields. 

Publishing process

Book initiated and editor appointed

Date completed: September 10th 2019

Applications to edit the book are assessed and a suitable editor is selected, at which point the process begins.

Chapter proposals submitted and reviewed

Deadline Extended: Open for Submissions

Potential authors submit chapter proposals ready for review by the academic editor and our publishing review team.

Approved chapters written in full and submitted

Deadline for full chapters: November 30th 2019

Once approved by the academic editor and publishing review team, chapters are written and submitted according to pre-agreed parameters

Full chapters peer reviewed

Review results due: February 18th 2020

Full chapter manuscripts are screened for plagiarism and undergo a Main Editor Peer Review. Results are sent to authors within 30 days of submission, with suggestions for rounds of revisions.

Book compiled, published and promoted

Expected publication date: April 18th 2020

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About the editor

Marcelo Larramendy

National University of La Plata

Marcelo L. Larramendy, PhD, serves as a professor of molecular cell biology at the School of Natural Sciences and Museum (National University of La Plata - UNLP, Argentina). He was appointed as senior researcher of the National Scientific and Technological Research Council of Argentina and was a former member of the Executive Committee of the Latin American Association of Environmental Mutagenesis, Teratogenesis and Carcinogenesis. He is the author of more than 450 contributions, including scientific publications, research communications, and conference papers worldwide. He is the recipient of several national and international awards. Prof. Larramendy is a regular lecturer at international A. Hollaender Courses organized by the IAEMS and is a former guest scientist at NIH (USA) and the University of Helsinki (Finland). He is an expert in genetic toxicology and has been a referee for more than 20 international scientific journals. He was a member of the International Panel of Experts at the International Agency for Research on Cancer (WHO, Lyon, France) in 2015 for the evaluation of DDT, 2,4-D, and lindane. Presently, Prof. Dr. Larramendy is the head of the Laboratory of Molecular Cytogenetics and Genotoxicology at the UNLP.

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Book chapters authored 2

Books edited 16

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