About the book
The increased life expectancy results in higher tissue degradation. Therefore, there is a need to develop new therapies to overcome aging and in several cases, diseases.
Hydroxyapatite (HA) is an important member of the calcium phosphate chemical family. It has been used in several medical applications for the past decades, due to its chemical similarity to the mineral phase of bone and high biocompatibility. Several studies demonstrated that bone mineral presents several ion substitutions, so in order to prepare a synthetic material with an even closer composition to bone mineral, HA has been prepared with the incorporation of several ions like, silicon or fluoride. These ions induced not only structural changes on HA lattice, but also on its biocompatibility.
Significant advances in nanotechnologies resulted in the preparation of HA in different forms, with a wider range of applications, from support to drug and gene delivery.
This book aims to collect the most relevant information regarding HA properties, modifications and its application in the biomedical field.