Open access peer-reviewed Edited Volume

Hydroxyapatite - Properties and Functions


Apatite Chemical and Physical Structure Hydrothermal Synthesis Synthesis from Biogenic Sources Mineralization Bone Structure Vascularization Resorption Silicon Improved BioactivityBone Substitute Drug and Gene Carrier

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About the book

The increased life expectancy results in higher tissue degradation. Therefore, there is a need to develop new therapies to overcome aging and in several cases, diseases.
Hydroxyapatite (HA) is an important member of the calcium phosphate chemical family. It has been used in several medical applications for the past decades, due to its chemical similarity to the mineral phase of bone and high biocompatibility. Several studies demonstrated that bone mineral presents several ion substitutions, so in order to prepare a synthetic material with an even closer composition to bone mineral, HA has been prepared with the incorporation of several ions like, silicon or fluoride. These ions induced not only structural changes on HA lattice, but also on its biocompatibility.
Significant advances in nanotechnologies resulted in the preparation of HA in different forms, with a wider range of applications, from support to drug and gene delivery.
This book aims to collect the most relevant information regarding HA properties, modifications and its application in the biomedical field.

Publishing process

Book initiated and editor appointed

Date completed: October 4th 2019

Applications to edit the book are assessed and a suitable editor is selected, at which point the process begins.

Chapter proposals submitted and reviewed

Deadline Extended: Open for Submissions

Potential authors submit chapter proposals ready for review by the academic editor and our publishing review team.

Approved chapters written in full and submitted

Deadline for full chapters: April 17th 2020

Once approved by the academic editor and publishing review team, chapters are written and submitted according to pre-agreed parameters

Full chapters peer reviewed

Review results due: July 6th 2020

Full chapter manuscripts are screened for plagiarism and undergo a Main Editor Peer Review. Results are sent to authors within 30 days of submission, with suggestions for rounds of revisions.

Book compiled, published and promoted

Expected publication date: September 4th 2020

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About the editor

Claudia Manuela da Cunha Ferreira Botelho

University of Minho

CM Botelho has a PhD in Science Engineering from Porto University. Most of her PhD research was carried out at Queen Mary London University; Cambridge University, UK and NAIST, Japan. Her work on the modulation of calcium phosphate ceramics aiming to develop custom-made ceramic prostheses for reconstructive surgery, resulted in a worldwide patent. She published several scientific papers and was invited to give several talks. CM Botelho was invited to be lecturer at Minho Univ. Her work was distinguished with several international prizes, like the European Award on Biomaterials and Tissue Engineering Doctoral Award. In 2015 she was elected President of the National Researcher Association of Science and Technology and since then she has actively worked on the development of scientific policies. For the past years, she focused on nanocarriers.

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As an Author Service Manager my responsibilities include monitoring and facilitating all publishing activities for authors and editors. From chapter submission and review, to approval and revision, copy-editing and design, until final publication, I work closely with authors and editors to ensure a simple and easy publishing process. I maintain constant and effective communication with authors, editors and reviewers, which allows for a level of personal support that enables contributors to fully commit and concentrate on the chapters they are writing, editing, or reviewing. I assist authors in the preparation of their full chapter submissions and track important deadlines and ensure they are met. I help to coordinate internal processes such as linguistic review, and monitor the technical aspects of the process. As an ASM I am also involved in the acquisition of editors. Whether that be identifying an exceptional author and proposing an editorship collaboration, or contacting researchers who would like the opportunity to work with IntechOpen, I establish and help manage author and editor acquisition and contact.

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