Open access peer-reviewed Edited Volume

Acute Liver Dysfunction - Principles and Practice

Vijay Gayam

Interfaith Medical Center


Liver Injury Cellular death pathways Blunt and penetrating trauma Infection-related Liver failure Liver Heart Interaction Hepatic cardiomyopathy Biochemical tests Radiology and other corroborative diagnostic measures Hepatic replacement Evidence-based guidelines for bridging strategy Hepatic replacement therapies Single pass albumin dialysis

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About the book

Once considered, as a seat of the soul by Babylonians, liver plays a puissant role in the metabolism of not only food but also various drugs and toxins. Although far-fetched from the thought of Hepatomancy, its unique anatomic location canoodling the GI tract and systemic circulation, it is a major organ for detoxification. It serves a multitude of functions that include synthetic, digestive and metabolic role, which cannot be simply replicated even in the sophisticated settings. Thus it appears prudent to preserve its integrity pending an irrevocable state induced by menacing insult. Any insults, be it traumatic, or circulatory dysfunction portends a poor prognosis if there is liver involvement. Understanding pathogenesis could envisage future therapies that might salvage or conceivably even completely shield the liver from the injury. Given its multifarious abilities, there is a myriad clinical sequela that can follow liver injury, the goals of therapies of which differ. This book describes the molecular pathogenesis and pathobiology of liver failure and presents an exhaustive discussion of evidence-based practices for supportive management including extracorporeal therapies. Although current treatments are far from every hepatologist dream of having an incredible power of regeneration as described in Prometheus of Greek mythology, it inevitably sets as a benchmark for further research.

Publishing process

Book initiated and editor appointed

Date completed: August 7th 2019

Applications to edit the book are assessed and a suitable editor is selected, at which point the process begins.

Chapter proposals submitted and reviewed

Deadline Extended: Open for Submissions

Potential authors submit chapter proposals ready for review by the academic editor and our publishing review team.

Approved chapters written in full and submitted

Deadline for full chapters: October 27th 2019

Once approved by the academic editor and publishing review team, chapters are written and submitted according to pre-agreed parameters

Full chapters peer reviewed

Review results due: January 15th 2020

Full chapter manuscripts are screened for plagiarism and undergo a Main Editor Peer Review. Results are sent to authors within 30 days of submission, with suggestions for rounds of revisions.

Book compiled, published and promoted

Expected publication date: March 15th 2020

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About the editor

Vijay Gayam

Interfaith Medical Center

Dr. Vijay Bhaskar Reddy Gayam is currently practicing as an internist at Interfaith Medical Center in Brooklyn, New York, USA. He is also a Clinical Assistant Professor at the SUNY Downstate University Hospital and Adjunct Professor of Medicine at the American University of Antigua. He is a holder of an M.B.B.S. degree bestowed to him by Osmania Medical College and received his M.D. at Interfaith Medical Center. His career goals thus far have heavily focused on direct patient care, medical education, and clinical research. He currently serves in two leadership capacities; Assistant Program Director of Medicine at Interfaith Medical Center and as a Councilor for the American Federation for Medical Research. As a true academician and researcher, he has more than 50 papers indexed in international peer-reviewed journals. He has also presented numerous papers in multiple national and international scientific conferences. His areas of research interest include general internal medicine, gastroenterology and hepatology. He serves as an editor, editorial board member and reviewer for multiple international journals. His research on Hepatitis C has been very successful and has led to multiple research awards, including the “Equity in Prevention and Treatment Award” from the New York Department of Health Viral Hepatitis Symposium (2018) and the “Presidential Poster Award” awarded to him by the American College of Gastroenterology (2018). He was also awarded “Outstanding Clinician in General Medicine” by Venus International Foundation for his extensive research expertise and services, perform over and above the standard expected in the advancement of healthcare, patient safety and quality of care.

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