Open access peer-reviewed Edited Volume


Sonia Soloneski

National University of La Plata

An Assistant Professor of Molecular Cell Biology at the National University of La Plata (Argentina) that authored more than 380 contributions in the field, including scientific publications in peer-reviewed journals and research communications.


Marcelo L. Larramendy

National University of La Plata

Head of the Laboratory of Molecular Cytogenetics and Genotoxicology at the National University of La Plata (Argentina) and author of more than 450 contributions, including scientific publications, research communications, and conferences worldwide.A recipient of several national and international awards.


Biomarkers Safety Testing Pesticides Biomolecules Medical Devices Nanomaterials Drugs Radiation Apoptosis Autophagy Cytotoxicity Testing Standardized Procedures

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About the book

Toxicity testing is a significant part of the process of evaluation of the hazards and risks that different xenobiotics present to humans, animals or the environment. The cytotoxic response plays a major role in determining the potential toxicity of any xenobiotic, including e.g., nanoparticles, pesticides, biomolecules, medical devices, drugs and radiation, towards living organisms. The identification of cytotoxic properties may be crucial in helping to explain target cells and organ toxicity. There are many different as well as highly recommended types of bioassay for estimating the cellular response and the presence of dead cells. The selection of suitable cytotoxicity bioassays is crucial for the accurate assessment of xenobiotic toxicity, and more than one methodology may be required to understand the complete toxicity profile due to numerous sublethal cellular changes that may occur after a short period of exposure.

The book “Cytotoxicity” aims to present the rationale, strategies, methods, interpretations and recent advances in the in vitro toxicity, presenting both theoretical and practical aspects.

Publishing process

Book initiated and editor appointed

Date completed: September 7th 2020

Applications to edit the book are assessed and a suitable editor is selected, at which point the process begins.

Chapter proposals submitted and reviewed

Deadline for chapter proposals: October 5th 2020

Potential authors submit chapter proposals ready for review by the academic editor and our publishing review team.

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Approved chapters written in full and submitted

Deadline for full chapters: December 4th 2020

Once approved by the academic editor and publishing review team, chapters are written and submitted according to pre-agreed parameters

Full chapters peer reviewed

Review results due: February 22nd 2021

Full chapter manuscripts are screened for plagiarism and undergo a Main Editor Peer Review. Results are sent to authors within 30 days of submission, with suggestions for rounds of revisions.

Book compiled, published and promoted

Expected publication date: April 23rd 2021

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About the editor

Sonia Soloneski

National University of La Plata

Sonia Soloneski has a PhD in Natural Sciences and is an Assistant Professor of Molecular Cell Biology at the School of Natural Sciences and Museum of La Plata, National University of La Plata, Argentina. She is a member of the National Scientific and Technological Research Council (CONICET) of Argentina in the Genetic Toxicology field, the Latin American Association of Environmental Mutagenesis, Teratogenesis and Carcinogenesis (ALAMCTA), the Argentinean Society of Toxicology (ATA), the Argentinean Society of Genetics (SAG), the Argentinean Society of Biology (SAB) and the Society of Environmental Toxicology and Chemistry (SETAC). She has authored more than 380 contributions in the field, including scientific publications in peer-reviewed journals and research communications. She has served as review member for more than 30 scientific international journals. She has been plenary speaker in scientific conferences and member of scientific committees. She is a specialist in issues related to Genetic Toxicology, Mutagenesis, and Ecotoxicology.

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Book chapters authored 2

Books edited 5

Introducing your Author Service Manager

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As an Author Service Manager my responsibilities include monitoring and facilitating all publishing activities for authors and editors. From chapter submission and review, to approval and revision, copyediting and design, until final publication, I work closely with authors and editors to ensure a simple and easy publishing process. I maintain constant and effective communication with authors, editors and reviewers, which allows for a level of personal support that enables contributors to fully commit and concentrate on the chapters they are writing, editing, or reviewing. I assist authors in the preparation of their full chapter submissions and track important deadlines and ensure they are met. I help to coordinate internal processes such as linguistic review, and monitor the technical aspects of the process. As an ASM I am also involved in the acquisition of editors. Whether that be identifying an exceptional author and proposing an editorship collaboration, or contacting researchers who would like the opportunity to work with IntechOpen, I establish and help manage author and editor acquisition and contact.

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