Open access peer-reviewed Edited Volume

Statin Therapy

Maria Suciu

Victor Babeș University of Medicine and Pharmacy


Minodora Andor

Victor Babeș University of Medicine and Pharmacy


Endothelial Dysfunction Inflammation Statins Pharmacokinetic Aspects Statin-Associated Pleiotropy Cholesterol Statin Response Pharmacogenetics Variability Interactions Adverse Effects Adherence and Persistence Statin Therapy

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About the book

Nowadays, cardio and cerebrovascular diseases are the leading cause of mortality and morbidity in the world, representing a burden for both the individual and society. Changes in the patient's lipid profile, especially the increase in plasma levels of low-density lipoprotein (LDL-cholesterol), is unanimously recognized today as one of the most important cardiovascular risk factors that plays a major role in initiating the development of structural changes and vascular remodeling, and later as the trigger point for the atherosclerosis process. In the last decade, statin therapy having well-established benefits in primary and secondary prevention of coronary heart disease and stroke, has earned an important place in many of therapeutic guidelines for the management of these diseases, but also in the treatment of other forms of high-risk cardiovascular disease conditions.

This book aims to review the clinical and pharmacological issues regarding the statin therapy. The clinical issues should refer to the benefits and risks of statin therapy in relation with the indications and contraindications of this therapy. The Editors hope that this book will offer a comprehensive, updated, and current research perspectives on statin therapy for a wide range of people, from students, clinicians, practicing researchers, academics, PhD students and other health professionals. 

Publishing process

Book initiated and editor appointed

Date completed: October 3rd 2019

Applications to edit the book are assessed and a suitable editor is selected, at which point the process begins.

Chapter proposals submitted and reviewed

Deadline for chapter proposals: October 24th 2019

Potential authors submit chapter proposals ready for review by the academic editor and our publishing review team.

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Approved chapters written in full and submitted

Deadline for full chapters: December 23rd 2019

Once approved by the academic editor and publishing review team, chapters are written and submitted according to pre-agreed parameters

Full chapters peer reviewed

Review results due: March 12th 2020

Full chapter manuscripts are screened for plagiarism and undergo a Main Editor Peer Review. Results are sent to authors within 30 days of submission, with suggestions for rounds of revisions.

Book compiled, published and promoted

Expected publication date: May 11th 2020

All chapters are copy-checked and typesetted before being published. IntechOpen regularly submits its books to major databases for evaluation and coverage, including the Clarivate Analytics Book Citation Index in the Web of ScienceTM Core Collection. Other discipline-specific databases are also targeted, such as Web of Science's BIOSIS Previews.

About the editor

Maria Suciu

Victor Babeș University of Medicine and Pharmacy

Education and training - Degree of Doctor of Medical Sciences (by the Order of the Minister of Education and Research nr. 4360 / 30. 07. 2013); Field of Medicine, Cardiology specialty, Thesis title: 'The benefits of treatment with rosuvastatin on endothelial dysfunction in patients with essential hypertension'; 'Victor Babes' University of Medicine and Pharmacy, Faculty of Medicine, Department of Medical Semiology, Cardiology ASCAR, Timisoara, Romania. - From 01. 10. 2010 to 30.09. 2011: Master’s in Pharmacy entitled 'Management of pharmacotherapy in the elderly'; University of Medicine and Pharmacy 'Victor Babes', Faculty of Pharmacy, Department of Pharmacology and Clinical Pharmacy, Timisoara, Romania. - Physician (Bachelor's Degree in Medicine Diploma nr 191 / 20.10.1993); MD Family Medicine (by the Order of the Ministry of Health, nr. 846/2003); Specialist physician in Clinical Pharmacology (by the Order of the Ministry of Health, nr. 772/2000); Pharmacist (Bachelor's Degree in Pharmacy Diploma nr 593 / 22.11.2000); 'Victor Babes' University of Medicine and Pharmacy, Faculty of General Medicine, Faculty of Pharmacy, Timisoara, Romania. Professional experience - From 01 March 2007 to present: Assistant Professor at discipline of Pharmacology and Clinical Pharmacy, Faculty of Pharmacy, 'Victor Babes' University of Medicine and Pharmacy. Research activity: pharmacological studies regarding the efficacy and tolerability of different drugs in medical practice, the share of consumption of different drugs within special populations at risk, the role of the pharmacist in health care system and therapeutic education programs. - Publications: 5 specialty books; 1 book chapter in international publishing houses; 4 scientific papers published in extenso in ISI indexed journals, 22 scientific papers published in CNCSIS journals and BDI indexed, 19 abstracts published in the volumes of some scientific events, with ISBN/ISSN, 12 abstracts published in international journals ISI indexed.

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