About the book
Immune dysregulation remains is the major cause for the development of different kinds of diseases. In recent decades, flow cytometry has emerged as an essential tool for real-time analysis of the cellular components and understanding the intricacies of immunological pathways. Flow cytometry-based immunophenotyping has greatly facilitated the descriptive understanding of the immune cells as well as their subsets for a better understanding of the disease pathophysiology, development of biomarkers for diagnosis, and identification of potential therapeutic targets. In the field of cancer biology, flow cytometric application has opened the doors for the study of different stages of cancer and helped in tailoring the drug dosage for therapeutic benefits. Furthermore, different cutting-edge innovations in the field of flow cytometry have led to the identification of the immune cell signatures associated with diseases therefore, it has served as a robust, sensitive, and all-inclusive platform for understanding diseases and their management. The clinical application of flow cytometric-based assays covers a diverse range of diseases including infectious diseases, minimal residual disease, organ transplantation, immunodeficiency diseases, post-operative monitoring, hemorrhage, blood transfusion, T-cell cross-matching, and platelet analysis are to name a few.
This book aims to provide an insight into the flow cytometric modality for explaining the disease etiology. It will broadly cover the flow cytometric-based molecular applications, innovations, and recent biomedical advances in unveiling disease prognostics, diagnostics, immunopathology, and therapeutics.