Open access peer-reviewed Edited Volume

Schwann Cells

Stavros Baloyannis

Aristotle University of Thessaloniki


Schwann Cell Myelin Formation Multipotent Glial Cells Neural Crest Stem Cells Schwann Cell Plasticity Regeneration Nerve Injury Schwann Cell Transcript BiomarkersTissue Culture Nerve Growth Factors Schwann Cells in Chronic Neuropathies Demyelinating Schwann Cell

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About the book

Schwann cell is the principal cellular component of the peripheral nervous system (PNS), derived from the neural crest, which retains the multipotential capacities of the neuroepithelial cells in association with many essential properties of glial cells, including the myelin sheath formation of axons in the peripheral nerves. Schwann cells are characterized by high plasticity, which is a crucial factor for nerve regeneration in case of injury of peripheral nerves, providing vital trophic support to the neurons and ensheathing the myelin in demyelinated axons. In case of injury Schwann cells undergo many radical phenotypic changes activating the myelin breakdown initially and up-regulating of cytokines and neurotrophic factors in order to promote the regeneration of the injured axons and the viability of the nerve cells. The main neurological disorders involving Schwann cells are peripheral demyelinating conditions and Schwannomas.

In this book we will aim to describe (a) the procedure of myelination and remyelination in the PNS by Schwann cells, (b) the precursor cells and their role in the homeostatic mechanisms of the PNS, (c) the plasticity of Schwann cells, (d) the response of Schwann cells in nerve injury, (e) the properties of Schwann cells in tissue culture and their interactions with neurons and glia cells and (f) the pathology of Schwann cells in peripheral neuropathies including Guillain-Barre and Charcot-Marie-Tooth disease (CMT).

Publishing process

Book initiated and editor appointed

Date completed: October 29th 2019

Applications to edit the book are assessed and a suitable editor is selected, at which point the process begins.

Chapter proposals submitted and reviewed

Deadline Extended: Open for Submissions

Potential authors submit chapter proposals ready for review by the academic editor and our publishing review team.

Approved chapters written in full and submitted

Deadline for full chapters: May 10th 2020

Once approved by the academic editor and publishing review team, chapters are written and submitted according to pre-agreed parameters

Full chapters peer reviewed

Review results due: July 29th 2020

Full chapter manuscripts are screened for plagiarism and undergo a Main Editor Peer Review. Results are sent to authors within 30 days of submission, with suggestions for rounds of revisions.

Book compiled, published and promoted

Expected publication date: September 27th 2020

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About the editor

Stavros Baloyannis

Aristotle University of Thessaloniki

Stavros J.Baloyannis is Emeritus Professor of Neurology at Aristotelian University, Thessaloniki, Greece. He was born in Thessaloniki. He graduated from the School of Medicine, Aristotelian University, Thessaloniki, Greece. Postgraduate training (a) in Neurology, Aristotelian University and Institute of Neurology, Queen Square, London, (b) in Neuropathology, Institute of Neurology, Queen Square, Catholic University of Louvain, University of Pennsylvania, Philadelphia (c) in Neurootology and Neuropathology of Auditory pathway, Harvard University, (d) in Neuropathology and Experimental Neurology, University of Pennsylvania, (e) in Neuroimmunology, Yale University, New Haven. He has done research on blood brain barrier in dementias and demyelinating diseases, mitochondria in Alzheimer’s disease, synaptogenesis in vivo and in vitro, neuronal apoptosis in dementias and demyelinating diseases, dendritic pathology in dementias, pathology of Golgi apparatus in dementias. His special interests are: Neuroethics, Neurolinguistics, Philosophy of Neurosciences, Application of mathematics in Neurosciences, Neurology and the Art. He is a member of 60 scientific societies in Greece and abroad. He is a honorary member of the Academy of Hellenic Air Forces. President of the Society for the amelioration of the quality of life in chronic neurological diseases. President of the Orthodox Medical Association for Health and medical education in Africa. Visiting professor in Tufts University, Democretian University, Thrace, Aristotelian University, School of Theology, Aristotelian University, School of Philosophy. He is an author of 28 textbooks on Neurology, Neuropathology, Neuropsychology and of 723 peer-reviewed papers, published in Greek and International Journals on Neurology, Neuropathology, Neuroimmunology and Neuroethics. He organized 26 national and international congresses (Constantinople, Vienna, Alexandria, Odessa, Catania and Marseille). He participated in 612 international congresses on Neurology and Neuropathology. In 2014 he published a collection of poems and a second one in 2016. He is Head of the 1st Department of Neurology, Aristotelian University (1992-2011). Emeritus Professor of Neurology, Aristotelian University, Thessaloniki, Greece. He is a director of Research Institute for Alzheimer’s disease and ageing.

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Book chapters authored 6

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