About the book
BRCA1 and BRCA2 genes play an essential role to maintain the integrity of the cellular function to suppress the tumor. However, a simple mutation in the active and binding site of the proteins or the genes will guarantee to shift in functional features, structures, and most possibly creating dysfunctional proteins and genes. In this respect, mutations in proteins and genes that play a role in tumor suppression such as BRCA1 and BRCA2 could be fatal for a human. Thus, it will cause breast cancer. It is the main focus of this book because it is considered as ‘the emperor of all maladies’, and has a very significant mortality rate, especially for women. In this sense, the search for ‘smart drug design’ that adjusts itself to the dynamics of mutation is desirable for targeting the oncoprotein that causes breast cancer. Moreover, as prevention and cautionary measures, mutations data from genomics and proteomics instrument should be extracted to find the possible biomarkers for breast cancer. This book aims to provide clear and concise narration on the diagnosis, prevention, and curation of cancer-based upon the genomics and proteomics-based BRCA1 and BRCA2 mutation data.