Open access peer-reviewed Edited Volume

Dry Eye

Felicia M. Ferreri

University of Messina

A researcher with a long clinical experience in glaucoma diagnosis and treatment, dry eye, and anterior segment. Dr. Ferreri was interned at San Raffaele Hospital in Milan (Corneal Section) and at Hospital Careggi in Florence (pediatric ophthalmology diseases). She spent research periods in Seville ('Virginio del Rocio' hospital), Madrid ('San Carlos' hospital), Manchester ('The 'Bolton Hospital'), and Rio de Janeiro (Universidade Fluminense).


Epidemiological Studies Risk Factors in Dry Eye Age-Related Dry Eye Glaucoma and Dry Eye Inflammation and Dry Eye Next-Generation Drugs Approved Therapies Cyclosporine Tear Composition Surface Epithelial Disease Desiccation and Eye Irritation Tear Hyperosmolarity

Register your interest in contributing to this book

Collaborate with our community and contribute your knowledge.

About the book

Dry eye is a chronic inflammatory disease that depends on a myriad of extrinsic or intrinsic factors that promote an unstable and hyperosmolar tear film. Changes in tear composition (along with another systemic factor) lead to an inflammatory cycle that yields acute desiccation and, ultimately, leads to fast cell death, desquamation and implies that the cornea surface appears poorly lubricated.

Millions of people worldwide suffer from dry eye disease, which leads to poor quality of life. Currently, the major advances to fight against the dry eye are represented by cyclosporine and lifitegrast, two FDA-approved therapies that can block the activation of T cells as well as cytokine production. While these therapies are a main pharmacological breakthrough, further research is required to design novel (and more effective) drugs and commercialize them. We are also in a quest for advancing our diagnostic methods to early detect dry eye.

This book will aim to illustrate to a wide audience (consisting of ophthalmologists, MD students, pharmacologists, and orthoptics) the most recent advances in both the diagnosis and treatment of dry eye, the potential of new therapies as well as their main limitations and, finally, to describe novel but promising therapeutic approaches which are at the preclinical stage.

Publishing process

Book initiated and editor appointed

Date completed: November 27th 2020

Applications to edit the book are assessed and a suitable editor is selected, at which point the process begins.

Chapter proposals submitted and reviewed

Deadline Extended: Open for Submissions

Potential authors submit chapter proposals ready for review by the academic editor and our publishing review team.

Approved chapters written in full and submitted

Deadline for full chapters: February 23rd 2021

Once approved by the academic editor and publishing review team, chapters are written and submitted according to pre-agreed parameters

Full chapters peer reviewed

Review results due: May 14th 2021

Full chapter manuscripts are screened for plagiarism and undergo a Main Editor Peer Review. Results are sent to authors within 30 days of submission, with suggestions for rounds of revisions.

Book compiled, published and promoted

Expected publication date: July 13th 2021

All chapters are copy-checked and typesetted before being published. IntechOpen regularly submits its books to major databases for evaluation and coverage, including the Clarivate Analytics Book Citation Index in the Web of ScienceTM Core Collection. Other discipline-specific databases are also targeted, such as Web of Science's BIOSIS Previews.

About the editor

Felicia M. Ferreri

University of Messina

Felicia M. Ferreri graduated summa cum laude from University of Messina, Italy in 1998 and completed her ophthalmology residency at the Policlinico Universitario, Messina in 2002. She was interned at San Raffaele Hospital in Milan (Corneal Section) and at Hospital Careggi in Florence (pediatric ophthalmology diseases). She spent research periods in Seville ('Virginio del Rocio' hospital), Madrid ('San Carlos' hospital), Manchester ('The 'Bolton Hospital') and Rio de Janiero (Universidade Fluminense). She served as co-investigator for many national and international clinical trials. Since 2002, she is an Assistant Professor in Ophthalmology at the University of Messina. Her research interests are in the areas of glaucoma, neuro-ophthalmology, pediatric ophthalmology, and cataract. She authored more than 50 scientific papers.

View profile

Book chapters authored 2

Books edited 1


Book will be abstracted and indexed in