About the book
The field of brain neuromodulation is steadfastly burgeoning with advances in the mechanisms it induces, as well as its therapeutic application to neurological and psychiatric disorders. Brain neuromodulation refers to neuroengineering technologies through electrical, chemical, optogenetic, and electromagnetic approaches that interface to alter the nervous system’s activity with the goal to better activate, inhibit or, regulate it. A variety of invasive – implantable and non-invasive modalities have been developed yet, no single systems mechanism can characterize these neuromodulatory approaches and neuroengineering technologies, as each one operates on a different spatial and temporal scale.
The goal of this book is to provide an overview of existing and introduce new neuromodulatory approaches applied in animals and humans. This book will explore advances in the physiological mechanisms uncovered through neuromodulatory approaches via electrophysiology, cranial ultrasound, and deep brain stimulation in primates and mice; development and fabrication of neuroengineering devices to enhance the spatial and temporal resolution of existing technologies; and clinical applications of invasive and non-invasive modalities, such as deep brain stimulation, intracranial cortical stimulation, transcranial magnetic stimulation, transcranial direct current stimulation, and real-time fMRI neurofeedback stimulation. Within the next decade, the space of brain neuromodulation is poised to undergo a burst of therapeutic interventions aiming to neuro-rehabilitate neurological and psychiatric disorders but also to increase human performance.