About the book
Pancreatic cancer is a devastating disease and it is the fourth leading cause of cancer-related deaths in most developed countries. Despite advances in the understanding of pathogenic molecular alterations involved in pancreatic carcinogenesis, early diagnosis remains challenging. The vast majority of patients have poor prognosis as they are diagnosed at a late inoperable stage with locally advanced tumor or distant metastases when symptoms arise. Outcomes are much better for pancreatic neuroendocrine tumors. A better understanding of pancreatic cancer development and progression, modifying of risk factors and early diagnosis of precancerous conditions with proper screening and prevention become important as those factors may ultimately lead to more effective diagnostic and therapeutic strategies. Improving early diagnosis and strengthening the standardized comprehensive treatment remain the main focus of pancreatic cancer research. Surgery, chemotherapy and radiation therapy improve patients’ prognosis and survival. The major purpose of this book is to offer the reader a better understanding of the challenging aspects in pancreatic cancer and to provide a thorough guide for the best approaches in screening, diagnosis, treatment and follow-up of patients with pancreatic malignancies.