About the book
Recent Advances, New Perspectives, and Applications in the Treatment of Ovarian Cancer should present a review of the significant advances in tumor biology and the treatment of ovarian cancer. Ovarian cancer is a heterogeneous disease with multiple distinct molecular and clinical subtypes.
In the first part of this book, the molecular profiles especially of the high-grade ovarian cancer will be described, and especially the clinical implications will be discussed.
The second part of the book will focus on the role of cytoreductive surgery, especially concerning the significant shift from primary cytoreductive surgery to neoadjuvant chemotherapy followed by interval debulking surgery in patients with advanced ovarian cancer knowing that optimal debulking surgery with R0-resection remains the gold standard. In this context, the current data and recommendations for the use of HIPEC will be discussed.
Last but not least, the book will focus on systemic treatment beginning with chemotherapy like neoadjuvant strategies and ending with targeted treatment like PARP-inhibition and new aspects to immunobiological therapies.