Open access peer-reviewed Edited Volume

Recent Advances, New Perspectives and Applications in the Treatment of Ovarian Cancer

Michael Friedrich

HELIOS Klinikum Krefeld

Director of the HELIOS Klinikum Krefeld, a highly active academic researcher with an h index of 25, was previously affiliated with the University of Tübingen and the University of Aachen. Dr. Friedrich is a member of the ISSVD, ESGO, IGCS, ESMO, EUSOMA, ASCO, DGS, AGO, and the Society of Reconstructive Surgery in Gynecology (AWO-Gyn).


Molecular Profile BRCA Mutation Parp Inhibition Antiangiogenesis Checkpoint Inhibition Antihormonal Treatment Intraperitoneal Chemotherapy HIPEC Primary Debulking Surgery Interval Debulking Surgery Recurrent Ovarian Cancer Targeted Treatment

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About the book

Recent Advances, New Perspectives, and Applications in the Treatment of Ovarian Cancer should present a review of the significant advances in tumor biology and the treatment of ovarian cancer. Ovarian cancer is a heterogeneous disease with multiple distinct molecular and clinical subtypes.

In the first part of this book, the molecular profiles especially of the high-grade ovarian cancer will be described, and especially the clinical implications will be discussed.

The second part of the book will focus on the role of cytoreductive surgery, especially concerning the significant shift from primary cytoreductive surgery to neoadjuvant chemotherapy followed by interval debulking surgery in patients with advanced ovarian cancer knowing that optimal debulking surgery with R0-resection remains the gold standard. In this context, the current data and recommendations for the use of HIPEC will be discussed.

Last but not least, the book will focus on systemic treatment beginning with chemotherapy like neoadjuvant strategies and ending with targeted treatment like PARP-inhibition and new aspects to immunobiological therapies.

Publishing process

Book initiated and editor appointed

Date completed: March 9th 2022

Applications to edit the book are assessed and a suitable editor is selected, at which point the process begins.

Chapter proposals submitted and reviewed

Deadline Extended: Open for Submissions

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Approved chapters written in full and submitted

Deadline for full chapters: July 10th 2022

Once approved by the academic editor and publishing review team, chapters are written and submitted according to pre-agreed parameters

Full chapters peer reviewed

Review results due: September 28th 2022

Full chapter manuscripts are screened for plagiarism and undergo a Main Editor Peer Review. Results are sent to authors within 30 days of submission, with suggestions for rounds of revisions.

Book compiled, published and promoted

Expected publication date: November 27th 2022

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About the editor

Michael Friedrich

HELIOS Klinikum Krefeld

Dr. Friedrich is the Director of the Department of Obstetrics and Gynecology of the Academic Teaching Hospital Krefeld. He is the author of more than 150 publications, mainly original contributions in peer-reviewed journals concerning gynecological malignancies and breast cancer as well as vitamin d metabolism. His main field of research activities is dealing with vitamin d metabolism in gynecological malignancies and in breast cancer. Another field of expertise is the interaction of DNA-mismatch repair and resistance to chemotherapy in gynecological malignancies. Further main points are the interstitial brachytherapy for recurrences of cervical cancer, the use of innovative therapies in gynecological malignancies, the technique of sentinel lymph node in gynecological malignancies especially in vulvar cancer, and the use of intraoperative intraperitoneal chemotherapy (HIPEC) in ovarian cancer.

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Book chapters authored 1

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