About the book
Organoid technology is an interdisciplinary technique that uses stem cells' self-renewal and multi-differentiation abilities to self-organize into three-dimensional (3D) tissue-like structures termed organoids. Multiple tissue types, including the kidney, brain, lung, intestine, stomach, breast, and liver, have thrived in organoid culture. The potential for fundamental and translational research in cultivating organ-specific tissue organoids and disease modeling to mimic the physiology and intricacy of a tissue-specific disease is enormous. Given the disparities between animal models and human disease pathology, a paradigm shift toward the utilization of a 3D human organoid platform may aid in better understanding the human component of disease progression. The Organoids system offers insights into the human disease development process, signal interactions, cell-cell interactions, potential therapeutic targets, and drug screening and discovery. Genome editing, hybrid culture systems, biobank creation, and single-cell sequencing are examples of cutting-edge technologies that may help create more physiologically realistic human illness models, which can change drug discovery. The use of a person's own stem cells for customized disease modeling, organoid transplantation, and drug screening for precision treatment has become easier because of advances in biobanking.