Open access peer-reviewed Edited Volume

Polycystic Ovary Syndrome

Zhengchao Wang

Fujian Normal University

Dr. Zhengchao Wang is a Principal Investigator for the General Program (National Natural Science Foundation of China) He is also a team leader in the Fujian Provincial Key Laboratory for Developmental Biology and Neurosciences. Dr. Wang is a senior member of the China Physiological Society, China Zoological Society, and China Maternal and Child Health Association.


Follicle Stimulating Hormone Luteinizing Hormone Follicular Development Ovulatory Failure Hypoxia-Inducible F1 Non-coding RNA Insulin Receptor Substrate Reproductive Hormone Polycystic Ovary Follicular Fluid Granulosa Cells PCOS

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About the book

Polycystic ovary syndrome (PCOS) is a major health problem with a heterogeneous hormone-imbalance disorder that occurs in reproductive-aged women worldwide, which is characterized by hyperandrogenism, ovulatory process dysfunction and polycystic ovaries. PCOS is affected by various factors and there are no unique diagnostic criteria in different regions, due to the heterogeneity of clinical manifestations and endocrine system changes of PCOS. Therefore, it is often difficult to accurately diagnose women with PCOS, as the signs and symptoms of PCOS can vary among individuals. Although PCOS is usually diagnosed during the early reproductive years, but the precise pathogenesis of PCOS remains unclear. An increasing number of studies have demonstrated that the insulin signaling pathway has an important role in the pathophysiology of PCOS, including phosphatidylinositol 3-kinase and protein kinase B signaling, which is critically implicated in insulin resistance, androgen secretion, obesity and follicular development. PCOS manifests as defective ovarian steroid biosynthesis and hyperandrogenemia, and 50~70% of women with PCOS exhibit insulin resistance and are hyperinsulinemic, indicating that insulin resistance and hyperinsulinism may have an important role in the pathophysiology of PCOS.

This book will intend to provide the reader with a comprehensive overview of the current state-of-the-art in PCOS researches and to benefit the population of women with PCOS. At last, It is my hope that this book will be meaningful to the clinicians who care for women with PCOS and to the researchers who investigate the complexities of this disorder disease.

Publishing process

Book initiated and editor appointed

Date completed: September 7th 2021

Applications to edit the book are assessed and a suitable editor is selected, at which point the process begins.

Chapter proposals submitted and reviewed

Deadline for chapter proposals: October 5th 2021

Potential authors submit chapter proposals ready for review by the academic editor and our publishing review team.

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Approved chapters written in full and submitted

Deadline for full chapters: December 4th 2021

Once approved by the academic editor and publishing review team, chapters are written and submitted according to pre-agreed parameters

Full chapters peer reviewed

Review results due: February 22nd 2022

Full chapter manuscripts are screened for plagiarism and undergo a Main Editor Peer Review. Results are sent to authors within 30 days of submission, with suggestions for rounds of revisions.

Book compiled, published and promoted

Expected publication date: April 23rd 2022

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About the editor

Zhengchao Wang

Fujian Normal University

Dr Zhengchao Wang is a full professor at the College of Life Sciences, Fujian Normal University (China). He is a Principal Investigator for General Program for National Natural Science Foundation of China and Program for New Century Excellent Talents in University of Ministry of Education of China. He is also a team leader in the Fujian Provincial Key Laboratory for Developmental Biology and Neurosciences, Key Laboratory of Optoelectronic Science and Technology for Medicine of Ministry of Education. He obtained his PhD in 2008 and has a long teaching and research career. He has published 161 scientific papers in English or Chinese, participated in approximately 30 grants, and published 11 books as the editor in his specialty and related diseases.

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