About the book
The increase in life expectancy leads to an increase in the number and duration of chronic diseases, affecting the majority of people over 60. Consequently, the number of drugs that each patient takes for year increases, both for therapeutic and preventative purposes. Unfortunately, little is known about the damage that politherapies can cause in individual organisms, and when the drugs have been taken for a long time (i.e for decreased absorption or a modified metabolism).
Another area of uncertainty is the potential effect following the suspension/ interruption of some chronic therapies in defined clinical situations.
The purpose of this text is to highlight both the positive and negative aspects of polytherapy in elderly subjects and when it should be necessary to take into consideration the regulated suspension (deprescribing) of one or more drugs. In particular, it would be important reducing or avoiding the prevalence of negative effects, which can even accelerate cognitive or physical decay, leading sometimes to premature death.