Open access peer-reviewed Edited Volume

Fecal Microbial Transplantation - Recent Advances, New Perspectives and Applications

Luis Rodrigo

University of Oviedo

Co-editor:

Adolfo Suárez González

University of Oviedo

Covering

Clinical Applications Efficacy Clostridium Difficile FMT Fecal Transplant Microbiome Single Fecal Infusions Multiple Fecal Infusions Clinical Remission Donors Selection Quality of Life Immunocompromised Patients

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About the book

Fecal microbiota transplantation (FMT) is a method to directly change the recipient's gut microbiota to normalize the composition and gain a therapeutic benefit. The history of FMT has been traced back to the 4th century and has been highly regarded since 2013, when the United States Food and Drug Administration approved FMT for treating recurrent and refractory Clostridium difficile infection. Since then, the range of FMT applications extended rapidly and broadly not only in gastrointestinal disorders, but also in extra-gastrointestinal diseases. Donor selection with questionnaire, interview, blood tests, and stool examinations should be strictly performed before FMT to reduce and prevent occurrence of any adverse events. Step-by-step cautious fecal and recipient preparation along with adequately choosing delivery methods based on individual clinical situations are key points of the FMT process. Although current evidence seems to point-out that FMT as a generally safe therapeutic method with few adverse effects, the long-term outcomes of FMT have not been completely elucidated. Therefore, establishing periodicity and length of regular follow-up after FMT to monitor the clinical efficacy and long-term adverse events are other essential issues. In the future, we will look forward to personalized FMT for different patients and conditions according to varied hosts and diseases.

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About the editor

Luis Rodrigo

University of Oviedo

Dr. Luis Rodrigo MD is Emeritus Professor of Medicine at the University of Oviedo (Spain). He has been the Chief of Gastroenterology Service at the HUCA Hospital in Oviedo, for more than 40 years. He obtained his PhD in 1975 and has developed a long teaching and research career. He has published a total of 592 scientific papers, 404 written in English and the rest in Spanish. He has participated as main investigator in a total of 45 clinical trials. He has contributed actively to the formation of one hundred specialists in Gastroenterology working in his Hospital. He has written around 40 chapters in books of several subjects and has been the editor of 20 books in his research field.

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Book chapters authored 4

Books edited 13

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