About the book
Advances in tissue engineering and regenerative medicine as well as drug delivery system require designing 3D scaffolds with structural and functional similarities to native tissue. 3D scaffolds are fabricated using natural and synthetic materials in various forms depending upon the requirements of human tissue. Topographical features, mechanical, biochemical and physicochemical cues of 3D scaffolds are essentially important to regulate regenerated cell properties in vitro and/or in vivo. Moreover, scaffolds may require functionalization by integrating stimuli such as bioactive compounds (growth factors, peptides, plant extracts etc.) to facilitate regeneration of tissues.
This book aims to highlight the novel and innovative techniques for designing and fabricating 3D scaffolds, their physical, chemical, and mechanical properties, the role of scaffolds on cellular behavior such as proliferation, migration, differentiation, and alignment of cells in vitro and in vivo tissue development, targeted delivery and sustain release of drugs and bioactive compounds, and development of acellular tissue substitutes.
The scope of this book will include, but will not be limited to, following topics:
- Fabrication and characterisation of 3D scaffolds
- Incorporation of bioactive compounds on materials for biofunctionalisation
- Cellular behaviours on functionalized biomaterials
- Development of tissue substitutes
- Drug delivery system for targeted delivery and sustain release
- Acellular tissue substitutes for tissue engineering and regenerative medicine