Open access peer-reviewed Edited Volume

Diabetic Eye Disease - From Therapeutic Pipeline to the Real World

Giuseppe Lo Giudice

Azienda Ospedaliera di Padova

A researcher in vitreoretinal surgical procedures and retinal disease and appointed head of the vitreoretinal and retinal service at San Antonio Hospital. Dr. Lo Giudice has more than 20 years of experience in clinical research, clinical trials, and laboratory research.


Fundus Photography Fundus Fluorescein Angiography Optical Coherence Tomography Macular Edema Proliferative Diabetic Retinopathy Laser Therapy Anti-VEGF Drugs Steroids Vitreous Hemorrhage Traction Retinal Detachment Miniinvasive Vitreoretinal Surgery Pathophysiology

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About the book

Diabetic retinopathy is a common and specific microvascular complication of diabetes. It is the leading cause of preventable blindness in working-aged people. Decades of research into the pathophysiology and management of diabetic retinopathy have revolutionized our understanding of the disease’s process. We know that this disease is going to be one of the defining illnesses of the current century. The aim of this book is to describe some of the most important features of diabetic retinopathy, from the pathogenesis of the disease with small retinal vessel microangiopathies that are able to produce extravasation with edema and ischemic phenomenon, to newly diagnostic test like wide field fundus photography and OCT angiography.

Among complications, both severe non proliferative and proliferative diabetic retinopathy, macular edema, glaucoma, cataract represent the real challenge in the treatment of diabetic eye disease; treatment by laser photocoagulation or intravitreal anti-VEGF injections represent the gold standard for the management of DME; however, DR, and DME continue to be major causes of vision loss. Patients and caregivers, as well as healthcare professionals, are affected by the high treatment burden of frequent injections, office visits, and patient monitoring. Real-world research shows that patients receive fewer intravitreal injections than the number required to maintain the vision and anatomic benefits seen in clinical trials, and thus, these individuals experience poorer outcomes.

Combined, these factors present an unmet need for novel treatments beyond anti-VEGF monotherapy that will provide patients with increased efficacy and durability in treating DR, and DME New therapeutic targets or longer-acting formulations may be the key to helping patients keep their disease under control.

Publishing process

Book initiated and editor appointed

Date completed: April 8th 2021

Applications to edit the book are assessed and a suitable editor is selected, at which point the process begins.

Chapter proposals submitted and reviewed

Deadline for chapter proposals: May 6th 2021

Potential authors submit chapter proposals ready for review by the academic editor and our publishing review team.

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Approved chapters written in full and submitted

Deadline for full chapters: July 5th 2021

Once approved by the academic editor and publishing review team, chapters are written and submitted according to pre-agreed parameters

Full chapters peer reviewed

Review results due: September 23rd 2021

Full chapter manuscripts are screened for plagiarism and undergo a Main Editor Peer Review. Results are sent to authors within 30 days of submission, with suggestions for rounds of revisions.

Book compiled, published and promoted

Expected publication date: November 22nd 2021

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About the editor

Giuseppe Lo Giudice

Azienda Ospedaliera di Padova

Dr. Giuseppe Lo Giudice obtained his medical degree at University of Messina, Italy. His ophthalmological residency was completed at the Department of Ophthalmology, University of Padua, Italy, After his residency training, he became an Assistant in Ophthalmology at Conegliano Hospital and after he became a fellow at the Ophthalmology Department of the Gironcoli Ophthalmic Centre, Conegliano, Treviso, Italy. Since 2007 he has been a Professor Assistant in Ophthalmology at San Antonio Hospital in Padua. His major field of interest is development of new treatments for retinal diseases (proliferative retinopathies, AMD, and diabetic retinopathy). He also has more than 20 years of experience in clinical research as well as in clinical trials and laboratory research. He has performed more than 7000 anterior segment surgery (cataract surgery, phacotrabeculectomy, trabeculectomy etc.) in the last 5 years. More than 1500 vitreoretinal surgeries due to several vitreoretinal diseases (ocular trauma, complicated cataract surgery, retinal pucker, retinal detachment, and vitreoretinal proliferative disease) have been also performed in the last 3 years at the San Antonio Hospital.

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Book chapters authored 2

Books edited 2

Introducing your Author Service Manager

Mr. Josip Knapic

As an Author Service Manager my responsibilities include monitoring and facilitating all publishing activities for authors and editors. From chapter submission and review, to approval and revision, copy-editing and design, until final publication, I work closely with authors and editors to ensure a simple and easy publishing process. I maintain constant and effective communication with authors, editors and reviewers, which allows for a level of personal support that enables contributors to fully commit and concentrate on the chapters they are writing, editing, or reviewing. I assist authors in the preparation of their full chapter submissions and track important deadlines and ensure they are met. I help to coordinate internal processes such as linguistic review, and monitor the technical aspects of the process. As an ASM I am also involved in the acquisition of editors. Whether that be identifying an exceptional author and proposing an editorship collaboration, or contacting researchers who would like the opportunity to work with IntechOpen, I establish and help manage author and editor acquisition and contact.

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